| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 35 | 35 | 11 | 14 | 4.33 | .276 | 1.12 | 7.5 | 2.5 | 8.8 | 216.0 | 181 | 109 | 104 | 27 | 61 | 212 | 2 | 0 | 0 | 0 | 22 | 5 | 0 | 3.58 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 66 | 32 | 32 | 13 | 13 | 4.69 | .331 | 1.45 | 7.8 | 5.3 | 4.6 | 201.2 | 174 | 111 | 105 | 24 | 119 | 103 | 3 | 0 | 0 | 1 | 16 | 6 | 3 | 5.39 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 27 | 2012 | L | 33 | 31 | 28 | 8 | 10 | 6.02 | .368 | 1.72 | 10.6 | 4.9 | 8.1 | 148.0 | 174 | 100 | 99 | 25 | 80 | 133 | 0 | 1 | 0 | 0 | 8 | 4 | 6 | 5.10 |
| SP | Appier, K.Appier, Kevin # >> | 26 | 1993 | R | 32 | 32 | 31 | 11 | 12 | 4.62 | .313 | 1.34 | 8.7 | 3.4 | 5.7 | 208.2 | 201 | 110 | 107 | 30 | 78 | 131 | 2 | 0 | 0 | 1 | 15 | 6 | 5 | 4.83 |
| RP | Frohwirth, T.Frohwirth, Todd >> | 29 | 1991 | R | 50 | 89 | 0 | 4 | 4 | 4.33 | .311 | 1.34 | 8.2 | 4.0 | 5.4 | 97.2 | 88 | 49 | 47 | 13 | 43 | 58 | 0 | 0 | 6 | 0 | 0 | 1 | 0 | 4.91 |
| RP | Wetteland, J.Wetteland, John >> | 27 | 1993 | R | 48 | 85 | 0 | 9 | 1 | 5.10 | .335 | 1.46 | 9.9 | 3.4 | 8.4 | 84.2 | 92 | 49 | 48 | 9 | 32 | 78 | 0 | 1 | 1 | 0 | 0 | 4 | 6 | 3.82 |
| RP | Wohlers, M.Wohlers, Mark >> | 25 | 1995 | R | 16 | 60 | 0 | 4 | 3 | 4.13 | .295 | 1.26 | 7.8 | 3.6 | 9.0 | 65.1 | 56 | 30 | 30 | 9 | 26 | 65 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 4.00 |
| SU | Devine, J.Devine, Joey >> | 25 | 2008 | R | 83 | 62 | 0 | 2 | 2 | 4.55 | .321 | 1.35 | 8.6 | 3.7 | 9.3 | 61.1 | 58 | 32 | 31 | 10 | 25 | 63 | 0 | 4 | 8 | 0 | 0 | 4 | 0 | 4.49 |
| CL | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 84 | 70 | 0 | 2 | 6 | 4.56 | .310 | 1.34 | 7.0 | 5.0 | 8.4 | 77.0 | 60 | 39 | 39 | 12 | 43 | 72 | 0 | 31 | 2 | 0 | 0 | 1 | 1 | 4.87 |
| SP | Lolich, M.Lolich, Mickey >> | 31 | 1971 | L | 14 | 29 | 5 | 4 | 6 | 5.11 | .332 | 1.48 | 9.6 | 3.7 | 6.4 | 123.1 | 131 | 77 | 70 | 18 | 51 | 88 | 1 | 2 | 1 | 0 | 2 | 2 | 2 | 4.76 |