| SP | Scherzer, M.Scherzer, Max >> | 34 | 2018 | R | 100 | 32 | 32 | 15 | 8 | 3.70 | .278 | 1.13 | 7.3 | 2.9 | 7.5 | 223.2 | 182 | 96 | 92 | 34 | 71 | 187 | 4 | 0 | 0 | 3 | 20 | 5 | 4 | 4.33 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 85 | 33 | 33 | 14 | 11 | 4.13 | .314 | 1.37 | 8.7 | 3.6 | 7.7 | 205.0 | 198 | 98 | 94 | 26 | 82 | 176 | 1 | 0 | 0 | 1 | 16 | 2 | 2 | 4.16 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 32 | 2017 | L | 47 | 30 | 27 | 11 | 9 | 4.22 | .308 | 1.31 | 8.4 | 3.4 | 5.9 | 181.1 | 168 | 96 | 85 | 23 | 69 | 118 | 0 | 0 | 0 | 0 | 16 | 5 | 5 | 4.57 |
| SP | Martinez, D.Martinez, Dennis >> | 36 | 1991 | R | 45 | 32 | 32 | 12 | 12 | 4.82 | .329 | 1.44 | 9.6 | 3.4 | 5.0 | 209.0 | 222 | 116 | 112 | 33 | 80 | 116 | 1 | 0 | 0 | 0 | 14 | 5 | 3 | 5.16 |
| SP | Rogers, S.Rogers, Steve # >> | 33 | 1982 | R | 41 | 30 | 30 | 9 | 11 | 4.89 | .323 | 1.40 | 10.2 | 2.5 | 5.4 | 193.1 | 218 | 107 | 105 | 27 | 53 | 115 | 3 | 0 | 0 | 1 | 12 | 6 | 3 | 4.54 |
| RP | Storen, D.Storen, Drew >> | 26 | 2014 | R | 52 | 77 | 0 | 5 | 5 | 5.68 | .345 | 1.55 | 11.1 | 2.8 | 5.6 | 76.0 | 94 | 49 | 48 | 13 | 24 | 47 | 0 | 1 | 5 | 0 | 0 | 2 | 7 | 5.01 |
| RP | Reardon, J.Reardon, Jeff >> | 27 | 1982 | R | 30 | 48 | 0 | 2 | 2 | 2.43 | .279 | 1.16 | 7.2 | 3.4 | 5.2 | 59.1 | 47 | 16 | 16 | 8 | 22 | 34 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.73 |
| SU | Cordero, C.Cordero, Chad # >> | 23 | 2005 | R | 59 | 53 | 0 | 4 | 5 | 4.18 | .287 | 1.19 | 7.7 | 3.2 | 5.3 | 60.1 | 51 | 28 | 28 | 8 | 21 | 35 | 0 | 3 | 8 | 0 | 0 | 1 | 0 | 4.67 |
| SP | Zimmermann, J.Zimmermann, Jordan >> | 26 | 2012 | R | 22 | 25 | 8 | 5 | 6 | 5.93 | .328 | 1.45 | 10.1 | 3.0 | 4.8 | 120.0 | 134 | 86 | 79 | 30 | 40 | 64 | 1 | 0 | 0 | 0 | 3 | 2 | 0 | 6.23 |