| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 92 | 13 | 13 | 2 | 6 | 4.33 | .312 | 1.33 | 9.5 | 2.6 | 8.4 | 95.2 | 100 | 47 | 46 | 17 | 27 | 89 | 0 | 0 | 0 | 0 | 5 | 3 | 7 | 4.40 |
| SP | Maine, J.Maine, John # >> | 25 | 2006 | R | 70 | 13 | 13 | 2 | 5 | 4.50 | .316 | 1.36 | 9.0 | 3.2 | 6.9 | 78.0 | 78 | 42 | 39 | 11 | 28 | 60 | 0 | 0 | 0 | 0 | 5 | 2 | 2 | 4.45 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 49 | 12 | 12 | 6 | 2 | 4.64 | .346 | 1.56 | 10.2 | 4.0 | 6.6 | 75.2 | 85 | 40 | 39 | 10 | 33 | 55 | 1 | 0 | 0 | 0 | 5 | 2 | 1 | 4.67 |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 47 | 12 | 12 | 4 | 4 | 4.71 | .333 | 1.43 | 8.9 | 4.1 | 7.3 | 72.2 | 71 | 40 | 38 | 4 | 33 | 58 | 1 | 0 | 0 | 1 | 6 | 5 | 2 | 3.69 |
| RP | Vizcaino, L.Vizcaino, Luis >> | 28 | 2002 | R | 47 | 25 | 0 | 1 | 5 | 7.16 | .357 | 1.63 | 9.7 | 5.3 | 10.0 | 27.2 | 29 | 24 | 22 | 7 | 16 | 30 | 0 | 3 | 5 | 0 | 0 | 1 | 0 | 6.04 |
| RP | Howell, J.Howell, J.P. >> | 25 | 2008 | L | 33 | 21 | 0 | 1 | 2 | 3.38 | .333 | 1.50 | 7.1 | 6.4 | 8.6 | 24.0 | 19 | 9 | 9 | 4 | 17 | 23 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 5.38 |
| RP | Farnsworth, K.Farnsworth, Kyle >> | 25 | 2001 | R | 21 | 15 | 0 | 1 | 3 | 7.90 | .339 | 1.54 | 9.7 | 4.8 | 11.1 | 13.2 | 14 | 13 | 12 | 4 | 7 | 16 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 6.15 |
| SP | Colon, B.Colon, Bartolo >> | 32 | 2005 | R | 22 | 1 | 0 | 0 | 0 | 0.00 | .333 | 1.50 | - | - | - | 0.2 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Matsuzaka, D.Matsuzaka, Daisuke >> | 28 | 2008 | R | 33 | 4 | 0 | 0 | 1 | 10.50 | .400 | 2.00 | 9.0 | 9.0 | 13.5 | 6.0 | 6 | 8 | 7 | 2 | 6 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 7.33 |