| SP | Harden, R.Harden, Rich † >> | 27 | 2008 | R | 95 | 29 | 29 | 14 | 7 | 3.35 | .289 | 1.19 | 6.4 | 4.3 | 10.1 | 174.2 | 123 | 65 | 65 | 19 | 84 | 195 | 0 | 0 | 0 | 0 | 21 | 6 | 2 | 3.73 |
| SP | Alvarez, W.Alvarez, Wilson # >> | 33 | 2003 | L | 74 | 28 | 28 | 4 | 8 | 4.60 | .321 | 1.38 | 10.0 | 2.4 | 7.3 | 121.1 | 135 | 66 | 62 | 16 | 32 | 98 | 0 | 0 | 0 | 0 | 1 | 5 | 3 | 4.02 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 56 | 28 | 27 | 10 | 10 | 5.30 | .317 | 1.37 | 9.5 | 2.9 | 6.4 | 158.0 | 166 | 96 | 93 | 31 | 51 | 113 | 0 | 1 | 0 | 0 | 14 | 3 | 3 | 5.15 |
| RP | Neshek, P.Neshek, Pat † >> | 26 | 2006 | R | 94 | 85 | 0 | 11 | 6 | 3.77 | .307 | 1.32 | 9.7 | 2.2 | 9.4 | 121.2 | 131 | 54 | 51 | 17 | 29 | 126 | 0 | 8 | 3 | 0 | 0 | 2 | 0 | 3.51 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 81 | 0 | 5 | 5 | 3.86 | .296 | 1.24 | 9.1 | 2.1 | 9.8 | 109.2 | 110 | 50 | 47 | 11 | 26 | 119 | 0 | 7 | 1 | 0 | 0 | 2 | 7 | 2.90 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 56 | 70 | 0 | 2 | 5 | 4.30 | .291 | 1.18 | 7.3 | 3.5 | 9.2 | 83.2 | 67 | 42 | 40 | 12 | 32 | 85 | 0 | 13 | 4 | 0 | 0 | 4 | 0 | 4.13 |
| RP | Otsuka, A.Otsuka, Akinori >> | 32 | 2004 | R | 46 | 56 | 0 | 3 | 3 | 4.16 | .316 | 1.33 | 7.9 | 4.0 | 8.3 | 67.0 | 59 | 33 | 31 | 8 | 30 | 62 | 0 | 1 | 4 | 0 | 0 | 4 | 0 | 4.22 |
| RP | Fuentes, B.Fuentes, Brian >> | 33 | 2008 | L | 33 | 53 | 0 | 4 | 3 | 2.35 | .299 | 1.27 | 8.3 | 3.3 | 8.9 | 72.2 | 66 | 26 | 19 | 11 | 26 | 71 | 0 | 3 | 4 | 0 | 0 | 1 | 2 | 4.14 |