| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 13 | 13 | 3 | 6 | 6.34 | .366 | 1.70 | 12.2 | 3.2 | 6.0 | 71.0 | 96 | 52 | 50 | 12 | 25 | 47 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 5.01 |
| SP | Peavy, J.Peavy, Jake # $$ >> | 26 | 2007 | R | 88 | 13 | 13 | 4 | 2 | 3.62 | .303 | 1.29 | 8.3 | 3.3 | 8.6 | 92.0 | 85 | 38 | 37 | 10 | 34 | 88 | 0 | 0 | 0 | 0 | 7 | 1 | 3 | 3.64 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 76 | 13 | 13 | 2 | 7 | 4.24 | .316 | 1.35 | 8.5 | 3.7 | 8.2 | 76.1 | 72 | 39 | 36 | 6 | 31 | 69 | 0 | 0 | 0 | 0 | 6 | 3 | 3 | 3.55 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 68 | 13 | 13 | 4 | 5 | 6.85 | .355 | 1.59 | 12.5 | 1.8 | 7.4 | 71.0 | 99 | 54 | 54 | 19 | 14 | 58 | 0 | 0 | 0 | 0 | 4 | 4 | 3 | 5.61 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 86 | 12 | 12 | 7 | 5 | 4.52 | .329 | 1.38 | 10.4 | 2.1 | 7.2 | 77.2 | 89 | 46 | 39 | 11 | 18 | 62 | 1 | 0 | 0 | 0 | 8 | 7 | 3 | 4.22 |
| CL | Saito, T.Saito, Takashi $ >> | 37 | 2007 | R | 100 | 28 | 0 | 3 | 1 | 3.38 | .307 | 1.33 | 9.0 | 3.1 | 11.2 | 29.1 | 29 | 11 | 11 | 3 | 10 | 36 | 0 | 18 | 2 | 0 | 0 | 0 | 0 | 2.90 |
| SU | Wagner, B.Wagner, Billy $$ >> | 32 | 2003 | L | 89 | 30 | 0 | 5 | 0 | 5.40 | .322 | 1.43 | 10.7 | 2.4 | 9.3 | 26.2 | 31 | 16 | 16 | 8 | 7 | 27 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 5.73 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 85 | 34 | 0 | 2 | 1 | 4.26 | .331 | 1.45 | 5.8 | 7.5 | 11.3 | 31.2 | 20 | 16 | 15 | 4 | 26 | 39 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.77 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 87 | 27 | 0 | 1 | 1 | 3.91 | .290 | 1.22 | 7.6 | 3.6 | 6.8 | 25.1 | 21 | 11 | 11 | 3 | 10 | 19 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.24 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 72 | 20 | 0 | 2 | 0 | 1.61 | .309 | 1.30 | 7.0 | 4.9 | 7.4 | 22.1 | 17 | 4 | 4 | 2 | 12 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.32 |
| RP | Perez, R.Perez, Rafael >> | 25 | 2007 | L | 64 | 33 | 0 | 0 | 2 | 3.80 | .324 | 1.44 | 9.0 | 4.3 | 10.6 | 23.2 | 23 | 10 | 10 | 1 | 11 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.65 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 59 | 16 | 0 | 0 | 0 | 6.06 | .430 | 2.27 | 13.5 | 7.3 | 12.4 | 16.1 | 24 | 11 | 11 | 4 | 13 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.94 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 52 | 4 | 0 | 0 | 1 | 36.00 | .586 | 4.25 | 36.0 | 2.3 | 4.5 | 4.0 | 16 | 16 | 16 | 4 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 15.75 |