| SP | Martinez, P.Martinez, Pedro † $$ >> | 29 | 2000 | R | 100 | 17 | 17 | 10 | 6 | 2.62 | .231 | 0.86 | 6.1 | 1.7 | 10.1 | 147.2 | 100 | 43 | 43 | 19 | 27 | 165 | 13 | 0 | 0 | 3 | 13 | 6 | 1 | 3.11 |
| SP | Peavy, J.Peavy, Jake † # >> | 26 | 2007 | R | 89 | 16 | 16 | 10 | 3 | 4.24 | .277 | 1.12 | 7.7 | 2.5 | 8.3 | 116.2 | 99 | 55 | 55 | 15 | 32 | 107 | 2 | 0 | 0 | 2 | 8 | 3 | 2 | 3.74 |
| SP | Williams, W.Williams, Woody >> | 36 | 2002 | R | 79 | 15 | 15 | 6 | 6 | 4.52 | .346 | 1.57 | 10.9 | 3.4 | 6.7 | 87.2 | 105 | 48 | 44 | 16 | 33 | 65 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 5.07 |
| RP | Balfour, G.Balfour, Grant † >> | 31 | 2008 | R | 90 | 37 | 0 | 5 | 0 | 4.31 | .304 | 1.29 | 7.6 | 4.2 | 10.4 | 39.2 | 33 | 19 | 19 | 11 | 18 | 45 | 0 | 10 | 1 | 0 | 0 | 1 | 1 | 5.82 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 79 | 23 | 0 | 1 | 2 | 6.08 | .333 | 1.39 | 8.0 | 4.8 | 10.4 | 26.2 | 23 | 18 | 18 | 5 | 14 | 30 | 0 | 5 | 0 | 0 | 0 | 3 | 0 | 5.15 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 69 | 14 | 0 | 0 | 1 | 4.20 | .308 | 1.27 | 8.4 | 3.0 | 9.6 | 15.0 | 14 | 7 | 7 | 4 | 5 | 16 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 5.53 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 13 | 0 | 1 | 1 | 3.86 | .282 | 1.18 | 6.0 | 5.0 | 8.0 | 18.2 | 12 | 8 | 8 | 0 | 10 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2.89 |