| SP | Johnson, R.Johnson, Randy # >> | 38 | 2001 | L | 97 | 13 | 13 | 4 | 5 | 4.71 | .309 | 1.33 | 8.9 | 3.2 | 8.8 | 91.2 | 90 | 48 | 48 | 10 | 32 | 89 | 2 | 0 | 0 | 1 | 6 | 1 | 3 | 3.56 |
| SP | Sheets, B.Sheets, Ben # >> | 26 | 2004 | R | 89 | 13 | 13 | 8 | 5 | 4.47 | .291 | 1.20 | 9.8 | 1.0 | 9.5 | 96.2 | 105 | 48 | 48 | 17 | 11 | 101 | 4 | 0 | 0 | 0 | 6 | 3 | 2 | 3.64 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 12 | 12 | 7 | 4 | 4.97 | .338 | 1.46 | 10.2 | 3.1 | 7.6 | 70.2 | 79 | 41 | 39 | 16 | 24 | 59 | 1 | 0 | 0 | 0 | 5 | 5 | 0 | 5.53 |
| SP | Zambrano, C.Zambrano, Carlos # >> | 24 | 2005 | R | 69 | 12 | 12 | 1 | 3 | 5.80 | .352 | 1.61 | 10.3 | 4.3 | 6.5 | 71.1 | 81 | 46 | 46 | 13 | 34 | 51 | 0 | 0 | 0 | 0 | 2 | 1 | 5 | 5.42 |
| SP | Maddux, G.Maddux, Greg # >> | 34 | 2000 | R | 57 | 12 | 12 | 2 | 8 | 5.87 | .354 | 1.63 | 12.2 | 2.6 | 5.6 | 79.2 | 107 | 52 | 52 | 17 | 23 | 49 | 2 | 0 | 0 | 0 | 3 | 1 | 2 | 5.47 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 86 | 26 | 0 | 1 | 2 | 3.41 | .343 | 1.49 | 7.8 | 5.6 | 10.2 | 37.0 | 32 | 14 | 14 | 6 | 23 | 42 | 0 | 4 | 3 | 0 | 0 | 3 | 0 | 4.95 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 69 | 18 | 0 | 0 | 2 | 5.40 | .318 | 1.40 | 8.6 | 4.1 | 12.2 | 20.0 | 19 | 12 | 12 | 2 | 9 | 27 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 2.95 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 58 | 12 | 0 | 0 | 0 | 6.10 | .354 | 1.65 | 14.4 | 0.9 | 9.0 | 10.1 | 16 | 7 | 7 | 5 | 1 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.80 |