| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 17 | 17 | 7 | 7 | 4.20 | .337 | 1.46 | 8.8 | 4.4 | 6.2 | 111.1 | 108 | 52 | 52 | 15 | 54 | 76 | 2 | 0 | 0 | 1 | 8 | 8 | 0 | 5.06 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 86 | 16 | 16 | 6 | 8 | 5.13 | .316 | 1.32 | 9.6 | 2.4 | 9.5 | 98.1 | 104 | 56 | 56 | 15 | 26 | 103 | 1 | 0 | 0 | 0 | 8 | 6 | 4 | 3.87 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 72 | 16 | 16 | 5 | 6 | 4.24 | .327 | 1.42 | 9.6 | 3.3 | 6.1 | 99.2 | 106 | 50 | 47 | 13 | 36 | 67 | 0 | 0 | 0 | 0 | 9 | 3 | 0 | 4.54 |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 42 | 16 | 16 | 4 | 9 | 6.63 | .351 | 1.61 | 10.9 | 3.7 | 8.4 | 92.1 | 111 | 68 | 68 | 15 | 38 | 86 | 1 | 0 | 0 | 0 | 4 | 1 | 2 | 4.52 |
| CL | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 100 | 27 | 0 | 1 | 2 | 3.99 | .285 | 1.19 | 9.0 | 1.9 | 9.3 | 29.1 | 29 | 13 | 13 | 4 | 6 | 30 | 0 | 12 | 3 | 0 | 0 | 0 | 0 | 3.34 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 88 | 43 | 0 | 2 | 3 | 4.72 | .308 | 1.28 | 8.3 | 3.3 | 7.2 | 55.1 | 51 | 30 | 29 | 8 | 20 | 44 | 0 | 0 | 1 | 0 | 0 | 3 | 2 | 4.55 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 84 | 37 | 0 | 1 | 0 | 2.58 | .288 | 1.15 | 7.2 | 3.2 | 6.4 | 45.1 | 36 | 14 | 13 | 4 | 16 | 32 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 4.00 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 75 | 27 | 0 | 1 | 2 | 3.30 | .313 | 1.33 | 10.2 | 1.8 | 9.0 | 30.0 | 34 | 12 | 11 | 3 | 6 | 30 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.00 |
| SU | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 50 | 21 | 0 | 0 | 1 | 4.87 | .351 | 1.62 | 11.7 | 3.2 | 7.2 | 20.1 | 26 | 12 | 11 | 4 | 7 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.05 |