| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 34 | 34 | 13 | 11 | 4.01 | .285 | 1.18 | 8.6 | 2.0 | 8.5 | 238.0 | 227 | 115 | 106 | 34 | 54 | 224 | 8 | 0 | 0 | 1 | 19 | 4 | 8 | 3.71 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 32 | 32 | 13 | 18 | 3.81 | .291 | 1.21 | 7.9 | 3.0 | 5.5 | 253.0 | 221 | 116 | 107 | 26 | 84 | 156 | 15 | 0 | 0 | 3 | 15 | 7 | 6 | 4.18 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 31 | 31 | 11 | 12 | 5.00 | .312 | 1.33 | 9.0 | 3.0 | 7.6 | 185.1 | 186 | 112 | 103 | 28 | 61 | 156 | 2 | 0 | 0 | 0 | 15 | 5 | 17 | 4.35 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 31 | 31 | 12 | 14 | 5.40 | .342 | 1.53 | 9.5 | 4.3 | 6.2 | 196.2 | 207 | 121 | 118 | 31 | 94 | 135 | 2 | 0 | 0 | 1 | 13 | 5 | 1 | 5.19 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 83 | 0 | 2 | 2 | 2.40 | .252 | 0.98 | 6.6 | 2.3 | 8.2 | 56.1 | 41 | 18 | 15 | 8 | 14 | 51 | 0 | 4 | 1 | 0 | 0 | 2 | 2 | 3.89 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 98 | 0 | 2 | 1 | 2.82 | .287 | 1.18 | 7.1 | 3.5 | 10.3 | 67.0 | 53 | 24 | 21 | 10 | 26 | 77 | 0 | 8 | 1 | 0 | 0 | 2 | 0 | 3.90 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 52 | 0 | 1 | 3 | 4.66 | .301 | 1.29 | 8.3 | 3.6 | 9.2 | 38.2 | 35 | 20 | 20 | 5 | 15 | 39 | 0 | 6 | 0 | 0 | 0 | 0 | 2 | 3.84 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 36 | 0 | 6 | 4 | 5.28 | .328 | 1.47 | 9.0 | 4.5 | 9.0 | 30.2 | 30 | 18 | 18 | 6 | 15 | 30 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 5.10 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 9 | 0 | 1 | 0 | 5.59 | .356 | 1.66 | 13.0 | 3.0 | 8.0 | 9.2 | 13 | 6 | 6 | 2 | 3 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.11 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 6 | 1 | 2 | 3 | 6.75 | .420 | 2.10 | 13.8 | 5.5 | 6.2 | 13.1 | 20 | 13 | 10 | 3 | 8 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.69 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 20 | 0 | 0 | 1 | 4.79 | .339 | 1.49 | 10.9 | 2.7 | 5.5 | 67.2 | 81 | 43 | 36 | 7 | 20 | 41 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 4.16 |