| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 15 | 15 | 6 | 4 | 2.88 | .283 | 1.19 | 8.2 | 2.5 | 9.5 | 97.0 | 88 | 34 | 31 | 6 | 27 | 102 | 0 | 0 | 0 | 0 | 13 | 0 | 2 | 2.54 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 17 | 15 | 1 | 4 | 4.27 | .336 | 1.51 | 8.6 | 5.0 | 6.6 | 86.1 | 82 | 44 | 41 | 9 | 48 | 63 | 0 | 1 | 0 | 0 | 8 | 1 | 3 | 4.60 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 15 | 15 | 3 | 4 | 6.72 | .369 | 1.70 | 9.7 | 5.7 | 7.0 | 68.1 | 73 | 53 | 51 | 12 | 43 | 53 | 1 | 0 | 0 | 0 | 5 | 4 | 3 | 5.81 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 52 | 0 | 6 | 3 | 3.56 | .306 | 1.33 | 6.7 | 5.2 | 11.5 | 43.0 | 32 | 17 | 17 | 4 | 25 | 55 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 3.40 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 43 | 0 | 3 | 2 | 4.62 | .333 | 1.42 | 7.9 | 5.1 | 10.7 | 48.2 | 42 | 25 | 25 | 4 | 27 | 57 | 0 | 3 | 2 | 0 | 0 | 4 | 0 | 3.65 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 31 | 0 | 3 | 1 | 3.89 | .333 | 1.47 | 4.8 | 8.7 | 11.6 | 34.2 | 18 | 15 | 15 | 5 | 33 | 44 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.32 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 38 | 0 | 2 | 1 | 4.91 | .313 | 1.34 | 7.6 | 4.5 | 8.4 | 44.0 | 37 | 25 | 24 | 8 | 22 | 41 | 0 | 0 | 7 | 0 | 0 | 1 | 1 | 5.07 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 40 | 0 | 7 | 2 | 2.81 | .325 | 1.44 | 7.9 | 5.1 | 9.9 | 51.1 | 45 | 16 | 16 | 3 | 29 | 56 | 0 | 11 | 3 | 0 | 0 | 0 | 0 | 3.27 |