| SP | Mathewson, C.Mathewson, Christy $$ >> | 28 | 1908 | R | 83 | 33 | 33 | 15 | 10 | 3.53 | .280 | 1.15 | 8.4 | 1.9 | 5.8 | 244.2 | 229 | 105 | 96 | 23 | 52 | 156 | 5 | 0 | 0 | 1 | 20 | 5 | 3 | 3.65 |
| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 32 | 32 | 11 | 13 | 4.41 | .318 | 1.38 | 8.6 | 3.8 | 8.7 | 202.0 | 192 | 108 | 99 | 30 | 86 | 195 | 0 | 0 | 0 | 0 | 16 | 4 | 3 | 4.34 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 32 | 32 | 7 | 12 | 6.24 | .333 | 1.50 | 10.7 | 2.9 | 10.1 | 168.2 | 199 | 121 | 117 | 35 | 54 | 189 | 0 | 0 | 0 | 0 | 12 | 0 | 5 | 4.42 |
| SP | Reulbach, E.Reulbach, Ed $$ >> | 24 | 1906 | R | 60 | 31 | 31 | 10 | 11 | 3.79 | .332 | 1.47 | 7.7 | 5.6 | 5.3 | 185.1 | 158 | 88 | 78 | 16 | 115 | 109 | 0 | 0 | 0 | 0 | 14 | 3 | 1 | 4.86 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 21 | 3 | 3 | 2 | 4.94 | .342 | 1.56 | 10.2 | 3.9 | 5.1 | 98.1 | 111 | 60 | 54 | 14 | 42 | 56 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 5.00 |
| CL | Hader, J.Hader, Josh # >> | 24 | 2018 | L | 94 | 63 | 0 | 6 | 8 | 3.24 | .273 | 1.11 | 6.7 | 3.4 | 10.6 | 66.2 | 49 | 30 | 24 | 11 | 25 | 78 | 0 | 36 | 3 | 0 | 0 | 1 | 0 | 3.98 |
| RP | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 93 | 86 | 0 | 6 | 8 | 4.20 | .296 | 1.25 | 7.7 | 3.6 | 9.7 | 115.2 | 99 | 55 | 54 | 15 | 46 | 124 | 0 | 4 | 3 | 0 | 0 | 1 | 3 | 3.77 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 57 | 0 | 3 | 1 | 3.70 | .314 | 1.37 | 7.6 | 4.8 | 10.2 | 58.1 | 49 | 24 | 24 | 4 | 31 | 66 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.22 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 27 | 0 | 2 | 3 | 7.90 | .401 | 1.98 | 14.7 | 3.3 | 11.0 | 27.1 | 44 | 27 | 24 | 7 | 10 | 33 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 5.15 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 28 | 0 | 0 | 0 | 4.58 | .329 | 1.34 | 7.5 | 4.6 | 5.8 | 37.1 | 31 | 20 | 19 | 10 | 19 | 24 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 7.16 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 31 | 31 | 9 | 17 | 5.50 | .337 | 1.49 | 10.8 | 2.7 | 4.7 | 199.2 | 238 | 137 | 122 | 31 | 60 | 105 | 5 | 0 | 0 | 1 | 11 | 7 | 3 | 4.98 |