| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 38 | 38 | 19 | 8 | 3.57 | .277 | 1.14 | 7.8 | 2.5 | 9.7 | 234.1 | 202 | 98 | 93 | 33 | 65 | 253 | 2 | 0 | 0 | 0 | 22 | 3 | 0 | 3.54 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 36 | 36 | 11 | 14 | 4.75 | .304 | 1.29 | 9.1 | 2.6 | 9.0 | 223.2 | 225 | 119 | 118 | 40 | 64 | 224 | 5 | 0 | 0 | 2 | 15 | 4 | 5 | 4.24 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 35 | 35 | 6 | 14 | 6.00 | .373 | 1.77 | 11.1 | 4.8 | 5.0 | 183.0 | 226 | 129 | 122 | 30 | 97 | 101 | 1 | 0 | 0 | 0 | 10 | 3 | 2 | 5.67 |
| SP | Marichal, J.Marichal, Juan † # >> | 29 | 1966 | R | 77 | 34 | 34 | 18 | 9 | 3.56 | .292 | 1.22 | 9.4 | 1.6 | 5.6 | 232.1 | 242 | 104 | 92 | 28 | 42 | 144 | 12 | 0 | 0 | 4 | 19 | 3 | 3 | 3.91 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 103 | 0 | 10 | 6 | 3.15 | .311 | 1.35 | 7.3 | 4.9 | 11.1 | 131.1 | 106 | 49 | 46 | 9 | 71 | 162 | 0 | 10 | 4 | 0 | 0 | 1 | 6 | 3.07 |
| RP | Percival, T.Percival, Troy # >> | 26 | 1995 | R | 83 | 92 | 0 | 7 | 11 | 5.70 | .322 | 1.39 | 7.5 | 5.1 | 8.8 | 113.2 | 94 | 78 | 72 | 25 | 64 | 110 | 0 | 8 | 7 | 0 | 0 | 4 | 2 | 5.73 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 81 | 71 | 0 | 4 | 1 | 5.16 | .331 | 1.46 | 9.0 | 4.1 | 7.7 | 89.0 | 89 | 59 | 51 | 19 | 41 | 76 | 0 | 2 | 4 | 0 | 0 | 2 | 3 | 5.52 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 58 | 0 | 3 | 3 | 4.29 | .305 | 1.29 | 8.6 | 3.0 | 7.4 | 71.1 | 68 | 37 | 34 | 7 | 24 | 58 | 0 | 0 | 1 | 0 | 0 | 2 | 4 | 3.75 |