| SP | Lolich, M.Lolich, Mickey >> | 28 | 1968 | L | 60 | 18 | 18 | 9 | 5 | 4.41 | .310 | 1.34 | 9.3 | 2.8 | 5.7 | 114.1 | 118 | 56 | 56 | 10 | 35 | 72 | 3 | 0 | 0 | 1 | 11 | 1 | 1 | 3.82 |
| SP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 85 | 17 | 17 | 1 | 3 | 4.75 | .313 | 1.33 | 8.8 | 3.1 | 7.7 | 55.0 | 54 | 29 | 29 | 7 | 19 | 47 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.09 |
| SP | Turnbull, S.Turnbull, Spencer >> | 28 | 2021 | R | 79 | 19 | 18 | 0 | 2 | 5.94 | .353 | 1.62 | 10.7 | 3.8 | 6.5 | 47.0 | 56 | 31 | 31 | 2 | 20 | 34 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.45 |
| SP | Flaherty, J.Flaherty, Jack >> | 28 | 2024 | R | 82 | 19 | 19 | 9 | 3 | 6.06 | .357 | 1.60 | 11.3 | 3.1 | 10.3 | 101.0 | 127 | 70 | 68 | 20 | 35 | 116 | 0 | 0 | 0 | 0 | 8 | 6 | 5 | 4.50 |
| SP | Skubal, T.Skubal, Tarik >> | 26 | 2023 | L | 96 | 20 | 18 | 1 | 2 | 6.38 | .339 | 1.54 | 11.4 | 2.4 | 8.1 | 48.0 | 61 | 35 | 34 | 6 | 13 | 43 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.65 |
| CL | Alburquerque, A.Alburquerque, Al † >> | 25 | 2011 | R | 62 | 47 | 0 | 9 | 0 | 2.19 | .286 | 1.20 | 6.2 | 4.7 | 10.6 | 61.2 | 42 | 16 | 15 | 2 | 32 | 72 | 0 | 2 | 1 | 0 | 0 | 0 | 6 | 2.64 |
| SU | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 65 | 45 | 0 | 5 | 2 | 2.34 | .278 | 1.16 | 7.5 | 2.9 | 6.5 | 77.0 | 64 | 20 | 20 | 6 | 25 | 56 | 0 | 2 | 3 | 0 | 0 | 0 | 7 | 3.53 |
| RP | Rondon, B.Rondon, Bruce >> | 25 | 2016 | R | 63 | 44 | 0 | 11 | 0 | 2.67 | .254 | 1.01 | 4.8 | 4.4 | 8.9 | 60.2 | 32 | 18 | 18 | 2 | 29 | 59 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 2.97 |
| RP | Greene, S.Greene, Shane >> | 30 | 2019 | R | 85 | 40 | 0 | 2 | 2 | 3.07 | .271 | 1.09 | 6.5 | 3.3 | 9.6 | 44.0 | 32 | 15 | 15 | 4 | 16 | 47 | 0 | 12 | 0 | 0 | 0 | 1 | 0 | 3.20 |
| RP | Chafin, A.Chafin, Andrew >> | 32 | 2022 | L | 43 | 50 | 0 | 7 | 0 | 3.27 | .317 | 1.39 | 7.6 | 5.0 | 7.6 | 52.1 | 44 | 22 | 19 | 3 | 29 | 44 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 3.73 |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 76 | 46 | 0 | 5 | 1 | 4.06 | .326 | 1.45 | 8.1 | 4.9 | 8.6 | 51.0 | 46 | 25 | 23 | 3 | 28 | 49 | 0 | 2 | 1 | 0 | 0 | 0 | 5 | 3.49 |
| RP | Walker, J.Walker, Jamie >> | 31 | 2002 | L | 53 | 50 | 0 | 3 | 1 | 3.91 | .315 | 1.36 | 7.9 | 4.5 | 6.1 | 50.2 | 44 | 23 | 22 | 5 | 25 | 34 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.50 |
| RP | Valverde, J.Valverde, Jose # >> | 31 | 2010 | R | 48 | 41 | 0 | 6 | 1 | 6.25 | .350 | 1.57 | 9.0 | 5.3 | 9.8 | 44.2 | 44 | 31 | 31 | 5 | 26 | 48 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 4.20 |