| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 90 | 23 | 23 | 9 | 9 | 3.94 | .285 | 1.19 | 7.4 | 3.3 | 5.4 | 153.0 | 126 | 68 | 67 | 16 | 56 | 91 | 1 | 0 | 0 | 1 | 13 | 1 | 1 | 4.29 |
| SP | Steele, E.Steele, Elmer † # >> | 22 | 1908 | R | 82 | 22 | 22 | 16 | 3 | 3.19 | .282 | 1.15 | 8.6 | 1.8 | 4.5 | 180.1 | 171 | 69 | 64 | 14 | 36 | 89 | 9 | 0 | 0 | 3 | 13 | 5 | 0 | 3.71 |
| SP | Cicotte, E.Cicotte, Eddie >> | 25 | 1909 | R | 47 | 21 | 21 | 7 | 7 | 5.07 | .333 | 1.48 | 8.2 | 5.2 | 4.3 | 99.1 | 90 | 56 | 56 | 7 | 57 | 47 | 1 | 0 | 0 | 1 | 9 | 2 | 3 | 4.76 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 64 | 0 | 7 | 2 | 3.38 | .246 | 0.92 | 6.0 | 2.3 | 9.1 | 69.1 | 46 | 27 | 26 | 11 | 18 | 70 | 0 | 4 | 6 | 0 | 0 | 4 | 1 | 4.00 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 99 | 55 | 0 | 1 | 2 | 3.02 | .269 | 1.06 | 5.6 | 4.0 | 8.8 | 59.2 | 37 | 20 | 20 | 3 | 26 | 58 | 0 | 8 | 1 | 0 | 0 | 3 | 0 | 3.17 |
| RP | Brasier, R.Brasier, Ryan >> | 30 | 2018 | R | 86 | 34 | 0 | 5 | 3 | 2.77 | .264 | 1.08 | 6.9 | 2.8 | 6.2 | 39.0 | 30 | 12 | 12 | 4 | 12 | 27 | 0 | 8 | 0 | 0 | 0 | 0 | 0 | 3.87 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 97 | 21 | 0 | 1 | 0 | 4.86 | .367 | 1.74 | 10.1 | 6.2 | 7.9 | 16.2 | 18 | 9 | 9 | 2 | 11 | 14 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4.94 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 69 | 59 | 0 | 2 | 0 | 2.08 | .274 | 1.13 | 6.1 | 4.2 | 9.4 | 43.1 | 29 | 10 | 10 | 2 | 20 | 45 | 0 | 4 | 2 | 0 | 0 | 0 | 2 | 2.91 |