| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 31 | 31 | 18 | 9 | 3.45 | .277 | 1.12 | 7.7 | 2.4 | 8.5 | 245.1 | 210 | 101 | 94 | 26 | 64 | 231 | 12 | 0 | 0 | 2 | 18 | 8 | 4 | 3.38 |
| SP | Steele, E.Steele, Elmer >> | 22 | 1908 | R | 82 | 30 | 30 | 14 | 12 | 4.04 | .302 | 1.28 | 9.4 | 2.1 | 4.4 | 223.0 | 233 | 104 | 100 | 24 | 52 | 108 | 11 | 0 | 0 | 5 | 15 | 4 | 0 | 4.18 |
| SP | Shore, E.Shore, Ernie # >> | 23 | 1914 | R | 71 | 29 | 29 | 15 | 10 | 4.23 | .295 | 1.24 | 8.3 | 2.9 | 4.2 | 217.0 | 200 | 103 | 102 | 25 | 70 | 102 | 5 | 0 | 0 | 0 | 16 | 2 | 5 | 4.55 |
| SP | O'Brien, B.O'Brien, Buck >> | 29 | 1911 | R | 74 | 28 | 28 | 0 | 3 | 4.13 | .310 | 1.33 | 7.4 | 4.7 | 3.8 | 69.2 | 57 | 32 | 32 | 7 | 36 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.09 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 98 | 85 | 0 | 14 | 3 | 2.94 | .255 | 1.02 | 6.4 | 2.8 | 10.3 | 88.2 | 63 | 32 | 29 | 7 | 27 | 101 | 0 | 9 | 1 | 0 | 0 | 1 | 3 | 2.69 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 67 | 0 | 5 | 1 | 2.38 | .238 | 0.93 | 7.1 | 1.3 | 8.9 | 75.2 | 59 | 20 | 20 | 11 | 11 | 74 | 0 | 5 | 3 | 0 | 0 | 1 | 0 | 3.41 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 97 | 82 | 0 | 4 | 1 | 3.35 | .244 | 0.93 | 4.8 | 3.7 | 8.7 | 53.2 | 28 | 22 | 20 | 5 | 22 | 51 | 0 | 6 | 3 | 0 | 0 | 2 | 4 | 3.66 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 95 | 59 | 0 | 3 | 3 | 4.58 | .308 | 1.33 | 7.9 | 4.1 | 9.3 | 57.0 | 50 | 29 | 29 | 9 | 26 | 59 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 4.35 |
| RP | Brasier, R.Brasier, Ryan >> | 30 | 2018 | R | 89 | 37 | 0 | 2 | 3 | 3.55 | .292 | 1.18 | 6.6 | 4.0 | 7.1 | 38.0 | 28 | 15 | 15 | 5 | 17 | 30 | 0 | 8 | 2 | 0 | 0 | 2 | 1 | 4.63 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 84 | 61 | 0 | 1 | 1 | 3.40 | .294 | 1.25 | 8.8 | 2.5 | 8.1 | 50.1 | 49 | 19 | 19 | 6 | 14 | 45 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 3.60 |