| SP | Bauer, T.Bauer, Trevor >> | 29 | 2020 | R | 90 | 32 | 32 | 4 | 18 | 6.31 | .362 | 1.66 | 10.5 | 4.5 | 8.4 | 168.1 | 196 | 119 | 118 | 17 | 84 | 156 | 1 | 0 | 0 | 0 | 14 | 6 | 6 | 4.07 |
| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 82 | 33 | 33 | 10 | 14 | 6.76 | .355 | 1.63 | 10.9 | 3.7 | 8.1 | 162.1 | 197 | 126 | 122 | 17 | 67 | 146 | 3 | 0 | 0 | 0 | 14 | 4 | 6 | 3.88 |
| SP | Gonsolin, T.Gonsolin, Tony >> | 28 | 2022 | R | 71 | 32 | 32 | 9 | 14 | 4.59 | .317 | 1.37 | 8.9 | 3.5 | 5.7 | 164.2 | 163 | 88 | 84 | 7 | 63 | 104 | 0 | 0 | 0 | 0 | 12 | 3 | 3 | 3.49 |
| RP | Clase, E.Clase, Emmanuel >> | 26 | 2024 | R | 77 | 78 | 0 | 6 | 6 | 3.25 | .253 | 0.99 | 6.9 | 2.1 | 5.1 | 105.1 | 80 | 44 | 38 | 5 | 24 | 59 | 0 | 1 | 2 | 0 | 0 | 3 | 2 | 3.27 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 71 | 57 | 0 | 1 | 5 | 3.05 | .298 | 1.25 | 7.3 | 4.0 | 9.2 | 59.0 | 48 | 20 | 20 | 1 | 26 | 60 | 0 | 30 | 6 | 0 | 0 | 1 | 3 | 2.56 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 66 | 66 | 0 | 5 | 4 | 3.92 | .286 | 1.16 | 8.6 | 1.9 | 8.3 | 85.0 | 81 | 37 | 37 | 12 | 18 | 78 | 0 | 0 | 2 | 0 | 0 | 3 | 0 | 3.74 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 65 | 55 | 0 | 1 | 3 | 4.14 | .299 | 1.24 | 7.4 | 3.9 | 9.9 | 58.2 | 48 | 31 | 27 | 5 | 25 | 64 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 3.31 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 67 | 14 | 0 | 2 | 3 | 2.92 | .315 | 1.30 | 8.6 | 3.4 | 2.6 | 24.2 | 23 | 13 | 8 | 1 | 9 | 7 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.33 |