| SP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 66 | 12 | 12 | 5 | 1 | 4.88 | .343 | 1.53 | 8.3 | 5.7 | 8.1 | 62.2 | 57 | 34 | 34 | 4 | 39 | 56 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 4.02 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 63 | 12 | 12 | 6 | 3 | 4.60 | .342 | 1.52 | 11.0 | 2.7 | 4.5 | 76.1 | 93 | 43 | 39 | 2 | 23 | 38 | 1 | 0 | 0 | 0 | 5 | 3 | 2 | 3.37 |
| SP | Bieber, S.Bieber, Shane >> | 25 | 2020 | R | 61 | 12 | 12 | 7 | 1 | 3.62 | .313 | 1.29 | 8.5 | 3.2 | 8.4 | 79.2 | 75 | 34 | 32 | 10 | 28 | 74 | 0 | 0 | 0 | 0 | 9 | 6 | 5 | 4.06 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 50 | 12 | 12 | 4 | 5 | 4.13 | .330 | 1.44 | 9.1 | 3.9 | 8.4 | 76.1 | 77 | 45 | 35 | 2 | 33 | 71 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 2.89 |
| CL | Hudson, B.Hudson, Bryan >> | 27 | 2024 | L | 68 | 26 | 0 | 0 | 0 | 1.44 | .265 | 1.04 | 6.1 | 3.2 | 8.3 | 25.0 | 17 | 4 | 4 | 0 | 9 | 23 | 0 | 22 | 1 | 0 | 0 | 1 | 0 | 2.36 |
| SU | Duffey, T.Duffey, Tyler >> | 29 | 2020 | R | 37 | 23 | 0 | 0 | 2 | 7.61 | .366 | 1.73 | 11.3 | 4.7 | 9.0 | 23.2 | 29 | 20 | 20 | 3 | 12 | 23 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 4.26 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 24 | 20 | 0 | 1 | 2 | 3.52 | .281 | 1.17 | 7.2 | 3.6 | 8.4 | 15.1 | 12 | 6 | 6 | 1 | 6 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.20 |
| RP | Hiller, J.Hiller, John >> | 30 | 1973 | L | 10 | 21 | 0 | 1 | 2 | 2.39 | .336 | 1.52 | 8.3 | 5.5 | 4.8 | 26.1 | 24 | 7 | 7 | 0 | 16 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.77 |
| SP | Darvish, Y.Darvish, Yu >> | 33 | 2020 | R | 14 | 1 | 0 | 0 | 0 | 13.50 | .600 | 4.50 | - | - | - | 0.2 | 3 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 9 | 10 | 0 | 1 | 2 | 8.14 | .387 | 1.85 | 14.3 | 2.6 | 6.8 | 24.1 | 38 | 24 | 22 | 1 | 7 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.04 |