| SP | Skubal, T.Skubal, Tarik † >> | 28 | 2025 | L | 100 | 33 | 33 | 21 | 9 | 3.03 | .263 | 1.05 | 7.3 | 2.1 | 10.7 | 228.2 | 185 | 79 | 77 | 25 | 54 | 271 | 0 | 0 | 0 | 0 | 24 | 6 | 2 | 2.84 |
| SP | Gilbert, L.Gilbert, Logan >> | 28 | 2025 | R | 91 | 33 | 33 | 10 | 10 | 5.09 | .321 | 1.40 | 9.2 | 3.5 | 10.8 | 180.1 | 183 | 110 | 102 | 35 | 70 | 215 | 0 | 0 | 0 | 0 | 10 | 3 | 5 | 4.36 |
| SP | Sanchez, C.Sanchez, Cristopher >> | 28 | 2025 | L | 82 | 32 | 32 | 13 | 12 | 4.81 | .319 | 1.37 | 9.9 | 2.5 | 10.3 | 196.2 | 215 | 111 | 105 | 37 | 54 | 225 | 4 | 0 | 0 | 1 | 17 | 8 | 5 | 4.11 |
| SP | Abbott, A.Abbott, Andrew >> | 26 | 2025 | L | 71 | 31 | 31 | 8 | 11 | 5.25 | .349 | 1.55 | 10.9 | 3.1 | 8.0 | 175.0 | 211 | 108 | 102 | 29 | 61 | 155 | 0 | 0 | 0 | 0 | 12 | 9 | 2 | 4.58 |
| CL | Miller, M.Miller, Mason † >> | 26 | 2025 | R | 98 | 70 | 0 | 4 | 7 | 3.62 | .273 | 1.11 | 6.2 | 3.9 | 12.7 | 64.2 | 44 | 30 | 26 | 5 | 28 | 90 | 0 | 40 | 3 | 0 | 0 | 1 | 0 | 2.56 |
| RP | Thielbar, C.Thielbar, Caleb $ >> | 38 | 2025 | L | 92 | 104 | 0 | 2 | 1 | 2.22 | .240 | 0.92 | 5.1 | 3.2 | 8.6 | 77.0 | 44 | 25 | 19 | 6 | 27 | 74 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 3.22 |
| RP | Suarez, R.Suarez, Robert $ >> | 34 | 2025 | R | 91 | 103 | 0 | 4 | 2 | 4.39 | .328 | 1.38 | 8.7 | 3.8 | 9.1 | 69.2 | 67 | 39 | 34 | 15 | 29 | 70 | 0 | 1 | 5 | 0 | 0 | 6 | 4 | 5.32 |
| RP | Clarke, T.Clarke, Taylor >> | 32 | 2025 | R | 87 | 71 | 0 | 2 | 2 | 2.58 | .288 | 1.13 | 8.4 | 1.8 | 7.3 | 59.1 | 55 | 21 | 17 | 8 | 12 | 48 | 0 | 0 | 4 | 0 | 0 | 5 | 2 | 4.00 |
| RP | Weaver, L.Weaver, Luke >> | 31 | 2025 | R | 83 | 52 | 0 | 8 | 0 | 3.10 | .318 | 1.34 | 6.6 | 5.5 | 11.2 | 49.1 | 36 | 17 | 17 | 6 | 30 | 61 | 0 | 3 | 1 | 0 | 0 | 3 | 0 | 4.12 |
| RP | Pomeranz, D.Pomeranz, Drew >> | 36 | 2025 | L | 72 | 95 | 0 | 3 | 2 | 4.57 | .323 | 1.39 | 9.1 | 3.4 | 11.4 | 67.0 | 68 | 36 | 34 | 10 | 25 | 85 | 0 | 2 | 1 | 0 | 0 | 3 | 4 | 3.66 |
| SP | Littell, Z.Littell, Zack >> | 29 | 2025 | R | 65 | 30 | 0 | 3 | 3 | 5.75 | .329 | 1.41 | 9.6 | 3.2 | 7.6 | 76.2 | 81 | 53 | 49 | 19 | 27 | 64 | 0 | 6 | 0 | 0 | 0 | 5 | 2 | 5.83 |