| SP | Hernandez, L.Hernandez, Livan >> | 30 | 1997 | R | 98 | 34 | 34 | 12 | 13 | 3.93 | .286 | 1.16 | 8.3 | 2.2 | 6.7 | 217.1 | 199 | 96 | 95 | 19 | 54 | 161 | 2 | 0 | 0 | 1 | 21 | 8 | 0 | 3.51 |
| SP | Burnett, A.Burnett, A.J. † >> | 29 | 2002 | R | 95 | 34 | 34 | 21 | 10 | 3.69 | .310 | 1.32 | 8.6 | 3.2 | 9.7 | 229.0 | 220 | 96 | 94 | 17 | 82 | 247 | 1 | 0 | 0 | 0 | 23 | 6 | 8 | 2.96 |
| SP | Penny, B.Penny, Brad † >> | 28 | 2001 | R | 92 | 34 | 34 | 15 | 13 | 3.92 | .291 | 1.20 | 8.4 | 2.4 | 6.7 | 241.1 | 225 | 112 | 105 | 20 | 64 | 180 | 5 | 0 | 0 | 0 | 20 | 8 | 3 | 3.48 |
| SP | Beckett, J.Beckett, Josh # >> | 26 | 2005 | R | 92 | 32 | 32 | 10 | 12 | 4.72 | .304 | 1.27 | 8.2 | 3.2 | 6.8 | 196.1 | 179 | 108 | 103 | 21 | 70 | 147 | 2 | 0 | 0 | 1 | 13 | 8 | 7 | 4.09 |
| SP | Clement, M.Clement, Matt >> | 32 | 2002 | R | 87 | 33 | 33 | 13 | 9 | 4.33 | .334 | 1.47 | 8.7 | 4.6 | 9.1 | 205.2 | 198 | 101 | 99 | 10 | 105 | 207 | 0 | 0 | 0 | 0 | 17 | 7 | 6 | 3.25 |
| CL | Spooneybarger, T.Spooneybarger, Tim † >> | 27 | 2003 | R | 98 | 58 | 0 | 1 | 1 | 2.08 | .242 | 0.94 | 5.8 | 2.7 | 7.1 | 56.1 | 36 | 14 | 13 | 2 | 17 | 44 | 0 | 50 | 4 | 0 | 0 | 1 | 1 | 2.86 |
| SU | Heredia, F.Heredia, Felix >> | 31 | 2000 | L | 94 | 63 | 0 | 1 | 5 | 3.49 | .296 | 1.23 | 7.6 | 3.7 | 9.1 | 69.2 | 58 | 27 | 27 | 6 | 28 | 70 | 0 | 5 | 6 | 0 | 0 | 2 | 1 | 3.41 |
| RP | Mantei, M.Mantei, Matt >> | 33 | 2003 | R | 90 | 72 | 0 | 7 | 5 | 3.87 | .349 | 1.60 | 9.9 | 4.6 | 10.3 | 81.1 | 89 | 35 | 35 | 4 | 41 | 93 | 0 | 0 | 6 | 0 | 0 | 1 | 2 | 2.90 |
| RP | Urbina, U.Urbina, Ugueth >> | 32 | 2003 | R | 81 | 60 | 0 | 3 | 5 | 2.18 | .241 | 0.91 | 4.4 | 3.9 | 7.8 | 70.1 | 34 | 17 | 17 | 5 | 30 | 61 | 0 | 0 | 1 | 0 | 0 | 3 | 2 | 3.60 |
| RP | Nunez, V.Nunez, Vladimir # >> | 31 | 2001 | R | 80 | 37 | 0 | 5 | 3 | 5.40 | .332 | 1.46 | 10.1 | 3.3 | 7.7 | 41.2 | 46 | 25 | 25 | 6 | 15 | 35 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.37 |
| RP | Kensing, L.Kensing, Logan >> | 24 | 2006 | R | 71 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Willis, D.Willis, Dontrelle >> | 24 | 2005 | L | 82 | 20 | 0 | 2 | 0 | 2.19 | .226 | 0.84 | 5.5 | 2.2 | 7.8 | 61.2 | 37 | 16 | 15 | 5 | 15 | 53 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.16 |
| SP | Sanchez, A.Sanchez, Anibal >> | 22 | 2006 | R | 86 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |