| SP | Beckett, J.Beckett, Josh >> | 28 | 2005 | R | 97 | 30 | 30 | 12 | 9 | 2.87 | .263 | 1.05 | 7.5 | 1.9 | 7.6 | 216.2 | 181 | 72 | 69 | 20 | 46 | 182 | 1 | 0 | 0 | 1 | 23 | 5 | 2 | 3.23 |
| SP | Hernandez, L.Hernandez, Livan # >> | 32 | 1997 | R | 96 | 30 | 30 | 10 | 9 | 2.90 | .252 | 0.99 | 7.2 | 1.7 | 7.2 | 205.0 | 163 | 71 | 66 | 15 | 39 | 165 | 0 | 0 | 0 | 0 | 23 | 5 | 0 | 2.99 |
| SP | Burnett, A.Burnett, A.J. † >> | 31 | 2002 | R | 95 | 29 | 29 | 14 | 11 | 3.06 | .302 | 1.26 | 6.8 | 4.5 | 10.1 | 205.2 | 156 | 75 | 70 | 14 | 103 | 230 | 4 | 0 | 0 | 2 | 20 | 8 | 11 | 3.27 |
| SP | Sanchez, A.Sanchez, Anibal † >> | 24 | 2006 | R | 94 | 29 | 29 | 16 | 8 | 3.29 | .293 | 1.21 | 8.0 | 3.0 | 7.3 | 202.2 | 179 | 78 | 74 | 16 | 67 | 163 | 4 | 0 | 0 | 1 | 17 | 6 | 6 | 3.50 |
| SP | Penny, B.Penny, Brad † >> | 30 | 2001 | R | 92 | 29 | 29 | 14 | 10 | 3.49 | .292 | 1.20 | 8.4 | 2.4 | 7.2 | 211.1 | 197 | 93 | 82 | 17 | 56 | 168 | 7 | 0 | 0 | 0 | 17 | 9 | 3 | 3.38 |
| CL | Spooneybarger, T.Spooneybarger, Tim † >> | 29 | 2003 | R | 99 | 58 | 0 | 3 | 1 | 3.51 | .269 | 1.08 | 7.5 | 2.3 | 7.9 | 59.0 | 49 | 23 | 23 | 1 | 15 | 52 | 0 | 43 | 7 | 0 | 0 | 1 | 3 | 2.27 |
| RP | Heredia, F.Heredia, Felix # >> | 33 | 2000 | L | 85 | 68 | 0 | 4 | 3 | 5.45 | .310 | 1.24 | 7.5 | 3.8 | 5.8 | 36.1 | 30 | 24 | 22 | 5 | 15 | 23 | 0 | 2 | 1 | 0 | 0 | 4 | 1 | 5.11 |
| RP | Kensing, L.Kensing, Logan >> | 26 | 2006 | R | 84 | 58 | 0 | 6 | 6 | 3.21 | .306 | 1.30 | 7.3 | 4.6 | 10.9 | 47.2 | 38 | 19 | 17 | 4 | 24 | 57 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.28 |
| RP | Mantei, M.Mantei, Matt >> | 35 | 2003 | R | 74 | 19 | 0 | 2 | 0 | 2.00 | .299 | 1.17 | 5.0 | 5.5 | 7.0 | 18.0 | 10 | 4 | 4 | 1 | 11 | 14 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.33 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 90 | 11 | 0 | 0 | 1 | 3.63 | .342 | 1.56 | 12.2 | 2.1 | 7.4 | 34.2 | 46 | 15 | 14 | 1 | 8 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.44 |