| SP | Johnson, R.Johnson, Randy † >> | 45 | 2004 | L | 100 | 29 | 29 | 13 | 13 | 3.27 | .284 | 1.15 | 8.1 | 2.3 | 8.8 | 195.1 | 175 | 76 | 71 | 22 | 50 | 190 | 4 | 0 | 0 | 3 | 20 | 7 | 1 | 3.39 |
| SP | Hernandez, F.Hernandez, Felix † >> | 22 | 2005 | R | 100 | 29 | 29 | 22 | 5 | 2.24 | .233 | 0.89 | 6.0 | 2.0 | 9.4 | 228.2 | 153 | 57 | 57 | 22 | 50 | 237 | 13 | 0 | 0 | 5 | 25 | 5 | 1 | 2.90 |
| SP | Garcia, F.Garcia, Freddy † >> | 32 | 2001 | R | 94 | 28 | 28 | 16 | 8 | 3.10 | .276 | 1.12 | 7.7 | 2.4 | 7.2 | 209.1 | 179 | 75 | 72 | 23 | 56 | 167 | 6 | 0 | 0 | 2 | 19 | 4 | 1 | 3.69 |
| CL | Soriano, R.Soriano, Rafael † >> | 29 | 2003 | R | 100 | 45 | 0 | 0 | 0 | 1.05 | .204 | 0.77 | 4.8 | 2.1 | 9.6 | 43.0 | 23 | 5 | 5 | 2 | 10 | 46 | 0 | 39 | 2 | 0 | 0 | 0 | 0 | 2.16 |
| RP | Pineiro, J.Pineiro, Joel † >> | 30 | 2001 | R | 98 | 56 | 0 | 5 | 1 | 1.39 | .224 | 0.84 | 6.0 | 1.6 | 6.8 | 84.1 | 56 | 13 | 13 | 7 | 15 | 63 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 3.19 |
| RP | Sherrill, G.Sherrill, George >> | 31 | 2007 | L | 98 | 51 | 0 | 1 | 0 | 2.60 | .320 | 1.34 | 6.7 | 5.7 | 8.0 | 27.2 | 20 | 8 | 8 | 4 | 17 | 24 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.26 |
| RP | Thornton, M.Thornton, Matt >> | 32 | 2008 | L | 95 | 29 | 0 | 0 | 3 | 2.65 | .250 | 1.00 | 5.3 | 3.7 | 8.5 | 17.0 | 10 | 5 | 5 | 2 | 7 | 16 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 3.88 |
| RP | Morrow, B.Morrow, Brandon >> | 24 | 2008 | R | 90 | 35 | 0 | 2 | 1 | 2.10 | .267 | 1.09 | 6.1 | 4.0 | 10.8 | 25.2 | 17 | 6 | 6 | 3 | 11 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.48 |
| RP | Rodriguez, E.Rodriguez, Eddy >> | 27 | 2004 | R | 88 | 39 | 0 | 2 | 2 | 3.78 | .270 | 1.09 | 7.9 | 2.1 | 9.0 | 47.2 | 41 | 20 | 20 | 5 | 11 | 47 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.15 |
| SP | Bailey, H.Bailey, Homer >> | 22 | 2007 | R | 50 | 1 | 0 | 1 | 0 | 0.00 | .333 | 1.50 | 9.0 | 9.0 | 18.0 | 1.1 | 1 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |