| SP | Kennedy, J.Kennedy, Joe >> | 29 | 2001 | L | 91 | 28 | 28 | 14 | 8 | 2.92 | .262 | 1.05 | 7.7 | 1.7 | 6.9 | 197.0 | 168 | 70 | 64 | 19 | 38 | 152 | 1 | 0 | 0 | 0 | 19 | 4 | 1 | 3.35 |
| SP | Shields, J.Shields, James † >> | 27 | 2007 | R | 89 | 28 | 28 | 10 | 11 | 3.28 | .257 | 1.01 | 7.5 | 1.6 | 7.7 | 214.1 | 178 | 84 | 78 | 30 | 39 | 183 | 6 | 0 | 0 | 2 | 16 | 5 | 6 | 3.73 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 82 | 28 | 28 | 9 | 7 | 3.51 | .305 | 1.30 | 7.7 | 4.1 | 9.4 | 161.1 | 137 | 67 | 63 | 17 | 73 | 168 | 0 | 0 | 0 | 0 | 13 | 2 | 1 | 3.68 |
| SP | Saunders, T.Saunders, Tony >> | 33 | 1997 | L | 88 | 28 | 28 | 8 | 9 | 3.76 | .314 | 1.36 | 8.5 | 3.8 | 6.6 | 174.2 | 164 | 77 | 73 | 24 | 73 | 128 | 0 | 0 | 0 | 0 | 18 | 3 | 4 | 4.63 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 100 | 80 | 0 | 7 | 6 | 3.16 | .288 | 1.18 | 6.5 | 4.1 | 9.9 | 94.0 | 68 | 38 | 33 | 8 | 43 | 103 | 0 | 11 | 5 | 0 | 0 | 3 | 0 | 3.38 |
| RP | Howell, J.Howell, J.P. >> | 25 | 2008 | L | 89 | 62 | 0 | 4 | 3 | 2.09 | .248 | 0.98 | 5.1 | 3.7 | 8.4 | 77.2 | 44 | 18 | 18 | 7 | 32 | 72 | 0 | 15 | 5 | 0 | 0 | 1 | 2 | 3.60 |
| RP | Colome, J.Colome, Jesus >> | 31 | 2004 | R | 93 | 62 | 0 | 6 | 4 | 3.10 | .283 | 1.18 | 6.5 | 4.1 | 8.2 | 87.0 | 63 | 31 | 30 | 11 | 40 | 79 | 0 | 9 | 3 | 0 | 0 | 0 | 6 | 4.21 |
| RP | McClung, S.McClung, Seth >> | 27 | 2003 | R | 80 | 32 | 0 | 6 | 3 | 2.44 | .317 | 1.34 | 7.1 | 5.1 | 7.1 | 51.2 | 40 | 14 | 14 | 7 | 29 | 40 | 0 | 5 | 1 | 0 | 0 | 3 | 3 | 5.10 |
| RP | Zambrano, V.Zambrano, Victor >> | 33 | 2001 | R | 75 | 19 | 0 | 1 | 1 | 4.05 | .341 | 1.50 | 8.6 | 5.0 | 10.4 | 20.0 | 19 | 9 | 9 | 2 | 11 | 23 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 3.80 |