| SP | Thompson, J.Thompson, Justin >> | 34 | 1997 | L | 91 | 28 | 28 | 9 | 16 | 3.99 | .282 | 1.16 | 8.1 | 2.4 | 6.6 | 209.2 | 187 | 94 | 93 | 32 | 56 | 154 | 5 | 0 | 0 | 0 | 18 | 4 | 1 | 4.38 |
| SP | Verlander, J.Verlander, Justin >> | 25 | 2007 | R | 88 | 28 | 28 | 7 | 14 | 4.45 | .302 | 1.27 | 8.6 | 2.9 | 6.9 | 186.0 | 177 | 97 | 92 | 36 | 59 | 142 | 3 | 0 | 0 | 1 | 16 | 5 | 2 | 5.02 |
| SP | Galarraga, A.Galarraga, Armando # >> | 26 | 2008 | R | 83 | 28 | 28 | 9 | 10 | 4.53 | .309 | 1.30 | 9.6 | 2.1 | 7.1 | 176.2 | 188 | 93 | 89 | 17 | 42 | 138 | 2 | 0 | 0 | 1 | 13 | 7 | 4 | 3.52 |
| SP | Bonderman, J.Bonderman, Jeremy >> | 26 | 2004 | R | 77 | 28 | 28 | 7 | 14 | 5.36 | .331 | 1.46 | 9.3 | 3.9 | 7.2 | 164.2 | 170 | 101 | 98 | 29 | 71 | 131 | 0 | 0 | 0 | 0 | 14 | 3 | 5 | 5.05 |
| SP | Weaver, J.Weaver, Jeff >> | 32 | 2002 | R | 74 | 27 | 27 | 7 | 15 | 6.42 | .348 | 1.56 | 11.3 | 2.8 | 7.3 | 162.2 | 203 | 122 | 116 | 38 | 51 | 132 | 0 | 0 | 0 | 0 | 11 | 7 | 2 | 5.49 |
| CL | Farnsworth, K.Farnsworth, Kyle † >> | 32 | 2005 | R | 96 | 42 | 0 | 0 | 2 | 2.18 | .295 | 1.23 | 7.7 | 3.5 | 10.1 | 41.1 | 35 | 14 | 10 | 0 | 16 | 46 | 0 | 33 | 5 | 0 | 0 | 1 | 0 | 2.00 |
| RP | Zumaya, J.Zumaya, Joel >> | 24 | 2007 | R | 88 | 85 | 0 | 1 | 1 | 2.17 | .263 | 1.07 | 5.4 | 4.2 | 7.3 | 87.0 | 52 | 23 | 21 | 3 | 41 | 71 | 0 | 1 | 1 | 0 | 0 | 0 | 9 | 3.23 |
| RP | Rodney, F.Rodney, Fernando >> | 31 | 2006 | R | 82 | 66 | 0 | 2 | 4 | 3.34 | .290 | 1.19 | 6.8 | 3.9 | 7.7 | 62.0 | 47 | 23 | 23 | 7 | 27 | 53 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 4.16 |
| RP | Santos, V.Santos, Victor >> | 32 | 2001 | R | 73 | 36 | 0 | 6 | 3 | 1.38 | .245 | 0.94 | 5.9 | 2.6 | 7.4 | 52.1 | 34 | 8 | 8 | 3 | 15 | 43 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.08 |
| SP | Redman, M.Redman, Mark >> | 34 | 2003 | L | 66 | 12 | 0 | 3 | 2 | 3.18 | .306 | 1.32 | 9.0 | 3.0 | 7.4 | 45.1 | 45 | 16 | 16 | 1 | 15 | 37 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 2.64 |