| SP | Thompson, J.Thompson, Justin † >> | 33 | 1997 | L | 93 | 22 | 22 | 11 | 9 | 2.78 | .258 | 1.02 | 7.1 | 2.1 | 6.3 | 178.0 | 140 | 58 | 55 | 22 | 42 | 125 | 8 | 0 | 0 | 2 | 15 | 4 | 0 | 3.98 |
| SP | Bonderman, J.Bonderman, Jeremy # >> | 25 | 2004 | R | 81 | 22 | 22 | 4 | 12 | 4.53 | .303 | 1.28 | 8.8 | 2.8 | 7.7 | 137.0 | 134 | 73 | 69 | 20 | 42 | 117 | 0 | 0 | 0 | 0 | 12 | 3 | 5 | 4.18 |
| SP | Verlander, J.Verlander, Justin >> | 24 | 2007 | R | 79 | 21 | 21 | 3 | 10 | 5.20 | .320 | 1.39 | 8.9 | 3.6 | 7.2 | 133.1 | 132 | 83 | 77 | 27 | 53 | 106 | 0 | 0 | 0 | 0 | 8 | 3 | 6 | 5.31 |
| SP | Weaver, J.Weaver, Jeff # >> | 31 | 2002 | R | 79 | 21 | 21 | 9 | 9 | 4.23 | .296 | 1.23 | 9.3 | 1.8 | 6.2 | 149.0 | 154 | 78 | 70 | 19 | 30 | 103 | 2 | 0 | 0 | 0 | 12 | 4 | 4 | 3.96 |
| SP | Redman, M.Redman, Mark >> | 33 | 2003 | L | 71 | 21 | 21 | 10 | 9 | 4.12 | .316 | 1.39 | 9.3 | 3.2 | 6.8 | 137.2 | 142 | 66 | 63 | 20 | 49 | 104 | 0 | 0 | 0 | 0 | 15 | 0 | 5 | 4.45 |
| CL | Farnsworth, K.Farnsworth, Kyle † >> | 31 | 2005 | R | 96 | 40 | 0 | 2 | 3 | 1.66 | .208 | 0.79 | 4.7 | 2.4 | 9.2 | 38.0 | 20 | 7 | 7 | 1 | 10 | 39 | 0 | 32 | 3 | 0 | 0 | 0 | 1 | 2.08 |
| RP | Rodney, F.Rodney, Fernando >> | 30 | 2006 | R | 85 | 62 | 0 | 3 | 0 | 2.01 | .254 | 0.99 | 5.1 | 3.9 | 8.4 | 62.2 | 35 | 14 | 14 | 3 | 27 | 58 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 3.16 |
| RP | Zumaya, J.Zumaya, Joel >> | 23 | 2007 | R | 81 | 20 | 0 | 2 | 2 | 2.75 | .366 | 1.68 | 9.5 | 6.2 | 9.0 | 19.2 | 20 | 6 | 6 | 0 | 13 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.21 |
| RP | Santos, V.Santos, Victor >> | 31 | 2001 | R | 76 | 14 | 0 | 2 | 0 | 1.61 | .264 | 1.03 | 4.9 | 4.5 | 4.9 | 22.1 | 12 | 4 | 4 | 2 | 11 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.73 |
| SP | Castillo, F.Castillo, Frank >> | 38 | 2000 | R | 52 | 4 | 0 | 1 | 0 | 4.50 | .288 | 1.21 | 7.7 | 3.2 | 5.1 | 14.0 | 12 | 7 | 7 | 1 | 5 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.86 |