| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 28 | 28 | 10 | 13 | 3.32 | .267 | 1.07 | 7.2 | 2.5 | 8.5 | 214.0 | 171 | 82 | 79 | 28 | 59 | 203 | 9 | 0 | 0 | 2 | 16 | 4 | 2 | 3.69 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 27 | 27 | 7 | 9 | 5.32 | .325 | 1.39 | 9.0 | 3.6 | 7.6 | 152.1 | 152 | 90 | 90 | 26 | 60 | 128 | 0 | 0 | 0 | 0 | 11 | 8 | 4 | 4.88 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 26 | 26 | 9 | 13 | 5.10 | .314 | 1.34 | 9.4 | 2.7 | 7.9 | 171.1 | 178 | 102 | 97 | 29 | 51 | 151 | 2 | 0 | 0 | 0 | 12 | 6 | 12 | 4.44 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 26 | 26 | 8 | 11 | 4.93 | .332 | 1.46 | 10.0 | 3.1 | 7.1 | 166.0 | 185 | 98 | 91 | 29 | 58 | 131 | 5 | 0 | 0 | 1 | 11 | 5 | 1 | 4.83 |
| RP | Capps, C.Capps, Carter $ >> | 24 | 2015 | R | 84 | 53 | 0 | 4 | 3 | 2.93 | .271 | 1.11 | 6.5 | 3.6 | 11.6 | 58.1 | 42 | 21 | 19 | 3 | 23 | 75 | 0 | 7 | 3 | 0 | 0 | 0 | 2 | 2.28 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 34 | 0 | 1 | 5 | 4.93 | .406 | 1.99 | 10.9 | 7.4 | 8.7 | 34.2 | 41 | 19 | 19 | 3 | 28 | 33 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 4.85 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 29 | 0 | 1 | 3 | 4.97 | .333 | 1.46 | 10.8 | 2.5 | 8.6 | 25.1 | 30 | 14 | 14 | 5 | 7 | 24 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 4.64 |