| SP | deGrom, J.deGrom, Jacob † # >> | 33 | 2021 | R | 100 | 32 | 32 | 13 | 8 | 3.38 | .261 | 1.04 | 7.4 | 2.0 | 8.5 | 223.2 | 183 | 86 | 84 | 26 | 50 | 210 | 1 | 0 | 0 | 0 | 23 | 4 | 0 | 3.36 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 32 | 32 | 14 | 13 | 3.53 | .279 | 1.13 | 8.0 | 2.1 | 5.5 | 245.0 | 219 | 99 | 96 | 26 | 57 | 151 | 14 | 0 | 0 | 3 | 17 | 9 | 4 | 3.96 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 32 | 32 | 16 | 10 | 4.15 | .294 | 1.24 | 8.4 | 2.7 | 8.1 | 223.1 | 209 | 111 | 103 | 26 | 67 | 200 | 8 | 0 | 0 | 0 | 18 | 3 | 5 | 3.66 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 29 | 29 | 17 | 8 | 3.56 | .289 | 1.20 | 7.2 | 3.6 | 4.1 | 217.2 | 174 | 86 | 86 | 16 | 88 | 100 | 10 | 0 | 0 | 5 | 18 | 4 | 4 | 4.31 |
| RP | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 94 | 76 | 0 | 4 | 1 | 2.05 | .227 | 0.85 | 5.3 | 2.4 | 8.9 | 101.0 | 59 | 24 | 23 | 11 | 27 | 100 | 0 | 17 | 1 | 0 | 0 | 3 | 1 | 3.33 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 12 | 0 | 2 | 1 | 1.96 | .345 | 1.58 | 8.5 | 6.0 | 5.0 | 18.1 | 17 | 8 | 4 | 2 | 12 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.33 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 41 | 11 | 0 | 2 | 1 | 4.75 | .277 | 1.11 | 7.5 | 2.5 | 8.2 | 53.0 | 44 | 28 | 28 | 7 | 15 | 48 | 0 | 1 | 0 | 0 | 0 | 2 | 6 | 3.87 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 23 | 0 | 2 | 3 | 3.13 | .291 | 1.20 | 4.9 | 6.1 | 8.4 | 31.2 | 17 | 11 | 11 | 4 | 21 | 29 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.94 |