| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 95 | 33 | 33 | 16 | 7 | 4.09 | .285 | 1.18 | 7.6 | 3.1 | 8.4 | 213.1 | 179 | 104 | 97 | 27 | 73 | 199 | 1 | 0 | 0 | 0 | 21 | 3 | 5 | 3.85 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 32 | 32 | 14 | 16 | 4.08 | .310 | 1.32 | 9.0 | 2.8 | 7.5 | 225.0 | 226 | 110 | 102 | 23 | 70 | 187 | 3 | 0 | 0 | 0 | 17 | 7 | 1 | 3.69 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 32 | 32 | 14 | 11 | 3.51 | .266 | 1.08 | 7.5 | 2.2 | 4.6 | 223.0 | 185 | 102 | 87 | 23 | 55 | 113 | 4 | 0 | 0 | 2 | 21 | 3 | 3 | 4.11 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 32 | 32 | 11 | 10 | 5.01 | .333 | 1.47 | 9.8 | 3.5 | 6.5 | 219.1 | 239 | 130 | 122 | 23 | 84 | 158 | 5 | 0 | 0 | 0 | 13 | 5 | 4 | 4.14 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 61 | 0 | 4 | 6 | 3.65 | .310 | 1.33 | 8.4 | 3.7 | 7.2 | 61.2 | 57 | 26 | 25 | 5 | 25 | 49 | 0 | 40 | 6 | 0 | 0 | 1 | 3 | 3.74 |
| RP | Hader, J.Hader, Josh # >> | 24 | 2018 | L | 93 | 72 | 0 | 3 | 2 | 3.86 | .314 | 1.38 | 7.4 | 5.0 | 9.2 | 56.0 | 46 | 28 | 24 | 6 | 31 | 57 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.02 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 76 | 0 | 1 | 2 | 5.25 | .321 | 1.38 | 8.6 | 3.9 | 6.3 | 60.0 | 57 | 35 | 35 | 12 | 26 | 42 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 5.60 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 43 | 0 | 3 | 0 | 2.66 | .278 | 1.13 | 7.0 | 3.4 | 9.9 | 40.2 | 31 | 13 | 12 | 2 | 15 | 44 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 2.65 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 29 | 0 | 3 | 0 | 4.13 | .301 | 1.29 | 6.4 | 5.3 | 5.6 | 24.0 | 17 | 11 | 11 | 3 | 14 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.13 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 10 | 0 | 1 | 0 | 2.53 | .289 | 1.22 | 9.0 | 2.7 | 8.1 | 10.2 | 10 | 3 | 3 | 0 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.10 |
| SU | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 42 | 0 | 0 | 3 | 2.59 | .306 | 1.32 | 7.9 | 4.2 | 8.6 | 41.2 | 36 | 14 | 12 | 3 | 19 | 39 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 3.44 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 31 | 31 | 8 | 18 | 5.18 | .338 | 1.49 | 10.1 | 3.4 | 4.7 | 194.2 | 218 | 115 | 112 | 28 | 73 | 101 | 1 | 0 | 0 | 1 | 15 | 7 | 4 | 5.07 |