| SP | Kershaw, C.Kershaw, Clayton $$ >> | 28 | 2016 | L | 99 | 13 | 13 | 3 | 7 | 4.90 | .326 | 1.45 | 10.2 | 3.0 | 8.0 | 82.2 | 93 | 52 | 45 | 12 | 27 | 73 | 1 | 0 | 0 | 0 | 5 | 0 | 1 | 4.11 |
| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 13 | 13 | 7 | 3 | 2.66 | .259 | 1.03 | 6.4 | 2.9 | 5.3 | 101.1 | 72 | 30 | 30 | 7 | 32 | 59 | 5 | 0 | 0 | 1 | 11 | 2 | 1 | 3.74 |
| SP | Leonard, D.Leonard, Dutch $$ >> | 22 | 1914 | L | 91 | 13 | 13 | 6 | 3 | 4.40 | .265 | 1.04 | 7.0 | 2.5 | 6.0 | 77.2 | 60 | 38 | 38 | 12 | 21 | 51 | 0 | 0 | 0 | 0 | 6 | 3 | 1 | 4.64 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 12 | 12 | 3 | 3 | 4.48 | .331 | 1.46 | 9.7 | 3.5 | 5.6 | 80.1 | 86 | 41 | 40 | 10 | 31 | 50 | 1 | 0 | 0 | 1 | 6 | 2 | 1 | 4.61 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 13 | 12 | 4 | 5 | 5.29 | .311 | 1.32 | 9.7 | 2.3 | 5.6 | 83.1 | 89 | 49 | 49 | 15 | 21 | 52 | 1 | 1 | 0 | 0 | 3 | 3 | 1 | 4.96 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 20 | 0 | 1 | 2 | 7.11 | .321 | 1.42 | 9.9 | 2.8 | 9.0 | 19.0 | 21 | 16 | 15 | 9 | 6 | 19 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 8.11 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 28 | 0 | 1 | 2 | 4.93 | .316 | 1.36 | 8.5 | 4.0 | 7.4 | 34.2 | 32 | 19 | 19 | 5 | 15 | 28 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.68 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 18 | 0 | 0 | 0 | 4.71 | .292 | 1.24 | 6.9 | 4.3 | 7.7 | 21.0 | 16 | 11 | 11 | 1 | 10 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.33 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 5 | 0 | 1 | 1 | 3.14 | .386 | 1.88 | 9.6 | 7.7 | 5.1 | 14.1 | 15 | 8 | 5 | 1 | 12 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.36 |