| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 33 | 33 | 9 | 16 | 3.83 | .271 | 1.10 | 6.9 | 3.0 | 10.1 | 230.0 | 177 | 103 | 98 | 37 | 77 | 259 | 6 | 0 | 0 | 0 | 22 | 3 | 2 | 3.88 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 96 | 33 | 33 | 16 | 6 | 3.73 | .292 | 1.20 | 7.1 | 3.7 | 9.4 | 229.1 | 180 | 96 | 95 | 33 | 95 | 240 | 2 | 0 | 0 | 1 | 22 | 9 | 6 | 4.14 |
| SP | Sanchez, A.Sanchez, Anibal >> | 34 | 2018 | R | 55 | 32 | 32 | 7 | 14 | 4.80 | .309 | 1.32 | 8.3 | 3.6 | 7.4 | 180.0 | 165 | 105 | 96 | 31 | 72 | 147 | 0 | 0 | 0 | 0 | 16 | 4 | 4 | 4.87 |
| SP | Porcello, R.Porcello, Rick >> | 27 | 2016 | R | 55 | 32 | 32 | 10 | 14 | 4.91 | .306 | 1.28 | 8.9 | 2.6 | 7.1 | 220.0 | 218 | 126 | 120 | 40 | 63 | 173 | 3 | 0 | 0 | 0 | 14 | 10 | 4 | 4.79 |
| SP | Fister, D.Fister, Doug >> | 27 | 2011 | R | 39 | 32 | 32 | 12 | 14 | 5.50 | .323 | 1.39 | 9.7 | 2.8 | 7.2 | 216.0 | 233 | 132 | 132 | 51 | 68 | 173 | 1 | 0 | 0 | 0 | 13 | 8 | 1 | 5.52 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 97 | 89 | 0 | 5 | 5 | 3.47 | .277 | 1.11 | 6.9 | 3.2 | 8.7 | 114.0 | 87 | 44 | 44 | 16 | 40 | 110 | 0 | 19 | 6 | 0 | 0 | 4 | 3 | 4.05 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 82 | 73 | 0 | 8 | 2 | 3.11 | .332 | 1.44 | 7.4 | 5.6 | 10.2 | 81.0 | 67 | 31 | 28 | 10 | 50 | 92 | 0 | 9 | 4 | 0 | 0 | 4 | 1 | 4.33 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 83 | 61 | 0 | 5 | 2 | 2.73 | .297 | 1.20 | 7.2 | 3.7 | 10.8 | 69.1 | 55 | 23 | 21 | 9 | 28 | 83 | 0 | 9 | 4 | 0 | 0 | 5 | 0 | 3.72 |
| RP | Villarreal, B.Villarreal, Brayan >> | 25 | 2012 | R | 38 | 30 | 0 | 1 | 5 | 4.15 | .316 | 1.36 | 7.4 | 5.0 | 7.9 | 34.2 | 28 | 21 | 16 | 7 | 19 | 30 | 0 | 6 | 0 | 0 | 0 | 1 | 2 | 5.68 |