| SP | deGrom, J.deGrom, Jacob >> | 35 | 2021 | R | 100 | 36 | 36 | 17 | 7 | 3.55 | .265 | 1.07 | 7.0 | 2.7 | 10.2 | 225.2 | 175 | 98 | 89 | 37 | 67 | 255 | 4 | 0 | 0 | 1 | 22 | 2 | 0 | 3.79 |
| SP | Javier, C.Javier, Cristian # >> | 27 | 2022 | R | 97 | 34 | 34 | 13 | 7 | 3.32 | .265 | 1.04 | 6.3 | 3.1 | 10.5 | 192.2 | 134 | 75 | 71 | 25 | 66 | 225 | 3 | 0 | 0 | 3 | 17 | 8 | 1 | 3.51 |
| RP | Jansen, K.Jansen, Kenley >> | 31 | 2017 | R | 68 | 76 | 0 | 6 | 3 | 2.77 | .249 | 0.98 | 6.9 | 2.0 | 11.1 | 87.2 | 67 | 28 | 27 | 9 | 19 | 107 | 0 | 4 | 4 | 0 | 0 | 1 | 1 | 2.57 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 26 | 2012 | R | 100 | 95 | 0 | 8 | 4 | 3.49 | .278 | 1.12 | 7.1 | 3.0 | 8.8 | 116.0 | 91 | 46 | 45 | 18 | 39 | 113 | 0 | 11 | 3 | 0 | 0 | 4 | 5 | 4.18 |
| RP | Clase, E.Clase, Emmanuel >> | 26 | 2022 | R | 89 | 78 | 0 | 3 | 5 | 2.57 | .238 | 0.90 | 5.4 | 2.7 | 8.2 | 98.0 | 59 | 32 | 28 | 7 | 29 | 89 | 0 | 12 | 2 | 0 | 0 | 4 | 0 | 3.12 |
| RP | Robertson, D.Robertson, David >> | 34 | 2017 | R | 48 | 8 | 0 | 3 | 1 | 0.93 | .147 | 0.52 | 4.0 | 1.0 | 8.0 | 9.2 | 4 | 1 | 1 | 0 | 1 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.56 |
| RP | Rivero, F.Rivero, Felipe # >> | 27 | 2017 | L | 81 | 129 | 0 | 4 | 2 | 5.12 | .324 | 1.42 | 9.1 | 3.7 | 8.3 | 77.1 | 78 | 46 | 44 | 10 | 32 | 71 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 4.13 |
| SP | Fernandez, J.Fernandez, Jose >> | 23 | 2014 | R | 96 | 11 | 5 | 2 | 0 | 5.58 | .361 | 1.66 | 11.7 | 3.6 | 8.7 | 30.2 | 39 | 19 | 19 | 6 | 12 | 29 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.97 |
| SP | Greinke, Z.Greinke, Zack >> | 34 | 2015 | R | 66 | 29 | 24 | 13 | 8 | 4.81 | .320 | 1.38 | 9.1 | 3.4 | 7.5 | 170.1 | 171 | 93 | 91 | 28 | 64 | 142 | 2 | 1 | 0 | 1 | 9 | 5 | 3 | 4.69 |
| SP | Nelson, R.Nelson, Roger >> | 27 | 1972 | R | 83 | 29 | 29 | 11 | 7 | 4.63 | .301 | 1.26 | 9.0 | 2.4 | 5.7 | 149.2 | 149 | 80 | 77 | 21 | 40 | 95 | 0 | 0 | 0 | 0 | 10 | 4 | 3 | 4.44 |