| SP | Scherzer, M.Scherzer, Max >> | 27 | 2021 | R | 86 | 33 | 33 | 11 | 13 | 4.43 | .298 | 1.24 | 8.3 | 2.9 | 9.5 | 205.0 | 188 | 101 | 101 | 38 | 67 | 216 | 2 | 0 | 0 | 0 | 18 | 6 | 2 | 4.37 |
| SP | McClanahan, S.McClanahan, Shane >> | 26 | 2022 | L | 75 | 33 | 33 | 7 | 18 | 5.83 | .321 | 1.39 | 9.2 | 3.3 | 8.7 | 194.2 | 199 | 129 | 126 | 41 | 72 | 188 | 0 | 0 | 0 | 0 | 12 | 5 | 7 | 5.00 |
| SP | Woodruff, B.Woodruff, Brandon >> | 29 | 2021 | R | 64 | 32 | 32 | 10 | 11 | 4.58 | .316 | 1.37 | 8.7 | 3.6 | 8.3 | 196.2 | 190 | 107 | 100 | 32 | 79 | 181 | 3 | 0 | 0 | 1 | 16 | 3 | 5 | 4.53 |
| RP | Wagner, B.Wagner, Billy >> | 29 | 1999 | L | 98 | 97 | 0 | 7 | 1 | 3.42 | .288 | 1.19 | 6.7 | 4.0 | 11.2 | 108.0 | 80 | 42 | 41 | 15 | 48 | 134 | 0 | 3 | 3 | 0 | 0 | 3 | 3 | 3.74 |
| RP | Boxberger, B.Boxberger, Brad >> | 27 | 2014 | R | 94 | 89 | 0 | 7 | 5 | 3.02 | .297 | 1.24 | 6.3 | 4.9 | 10.4 | 107.1 | 75 | 37 | 36 | 10 | 58 | 124 | 0 | 7 | 4 | 0 | 0 | 3 | 4 | 3.61 |
| RP | Dotel, O.Dotel, Octavio >> | 30 | 2002 | R | 61 | 74 | 0 | 1 | 5 | 4.10 | .311 | 1.31 | 8.3 | 3.5 | 10.1 | 83.1 | 77 | 38 | 38 | 11 | 32 | 93 | 0 | 12 | 5 | 0 | 0 | 4 | 6 | 3.78 |
| RP | Rodney, F.Rodney, Fernando >> | 36 | 2012 | R | 60 | 50 | 0 | 4 | 3 | 2.70 | .279 | 1.14 | 7.1 | 3.2 | 8.5 | 53.1 | 42 | 20 | 16 | 4 | 19 | 50 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 3.23 |
| RP | Gossage, R.Gossage, Rich >> | 26 | 1977 | R | 50 | 36 | 0 | 5 | 2 | 2.68 | .298 | 1.23 | 6.7 | 4.5 | 6.8 | 50.1 | 37 | 18 | 15 | 4 | 25 | 38 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 4.14 |
| RP | McHugh, C.McHugh, Collin >> | 32 | 2018 | R | 33 | 26 | 0 | 1 | 1 | 5.04 | .336 | 1.44 | 8.6 | 4.3 | 9.0 | 25.0 | 24 | 14 | 14 | 5 | 12 | 25 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.28 |
| SP | Tanana, F.Tanana, Frank >> | 24 | 1976 | L | 46 | 9 | 0 | 1 | 0 | 4.50 | .250 | 1.00 | 8.1 | 0.9 | 8.1 | 10.0 | 9 | 5 | 5 | 3 | 1 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.40 |