| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 10 | 10 | 5 | 3 | 5.00 | .285 | 1.17 | 9.1 | 1.4 | 8.4 | 72.0 | 73 | 41 | 40 | 10 | 11 | 67 | 2 | 0 | 0 | 1 | 6 | 2 | 0 | 3.49 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 10 | 10 | 6 | 3 | 5.01 | .342 | 1.50 | 9.1 | 4.4 | 4.1 | 70.0 | 71 | 40 | 39 | 5 | 34 | 32 | 1 | 0 | 0 | 0 | 5 | 4 | 1 | 4.64 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 2 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 0.0 | 1.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 93 | 20 | 0 | 2 | 2 | 4.24 | .333 | 1.46 | 9.0 | 4.3 | 8.6 | 23.1 | 23 | 11 | 11 | 3 | 11 | 22 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 4.35 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 20 | 0 | 2 | 2 | 4.29 | .300 | 1.29 | 10.3 | 1.3 | 7.7 | 21.0 | 24 | 11 | 10 | 0 | 3 | 18 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 1.71 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 10 | 0 | 0 | 0 | 2.89 | .378 | 1.71 | 11.0 | 5.0 | 6.0 | 9.1 | 11 | 3 | 3 | 1 | 5 | 6 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.11 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 62 | 8 | 0 | 0 | 0 | 4.50 | .265 | 1.08 | 6.8 | 3.0 | 3.8 | 12.0 | 9 | 6 | 6 | 1 | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.25 |