| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 94 | 34 | 34 | 14 | 12 | 3.60 | .285 | 1.18 | 7.6 | 3.0 | 6.7 | 249.2 | 210 | 107 | 100 | 31 | 84 | 186 | 5 | 0 | 0 | 1 | 25 | 5 | 1 | 4.20 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 71 | 33 | 33 | 7 | 19 | 6.20 | .350 | 1.59 | 10.9 | 3.5 | 6.9 | 188.2 | 227 | 138 | 130 | 40 | 73 | 144 | 3 | 0 | 0 | 0 | 15 | 5 | 7 | 5.48 |
| SP | Beckett, J.Beckett, Josh # >> | 31 | 2011 | R | 56 | 32 | 32 | 11 | 9 | 3.97 | .299 | 1.24 | 8.0 | 3.2 | 7.9 | 201.2 | 179 | 93 | 89 | 21 | 72 | 176 | 0 | 0 | 0 | 0 | 18 | 7 | 4 | 3.79 |
| SP | Oswalt, R.Oswalt, Roy # >> | 33 | 2010 | R | 53 | 32 | 32 | 9 | 14 | 5.69 | .332 | 1.47 | 9.8 | 3.5 | 6.8 | 186.2 | 203 | 128 | 118 | 22 | 72 | 141 | 0 | 0 | 0 | 0 | 11 | 3 | 2 | 4.23 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 94 | 107 | 0 | 2 | 3 | 3.27 | .272 | 1.11 | 6.2 | 3.9 | 9.4 | 93.2 | 64 | 35 | 34 | 6 | 40 | 97 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 3.08 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 75 | 107 | 0 | 2 | 6 | 3.75 | .300 | 1.28 | 7.5 | 4.0 | 8.4 | 127.1 | 106 | 55 | 53 | 19 | 57 | 119 | 0 | 12 | 6 | 0 | 0 | 1 | 2 | 4.44 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 48 | 66 | 0 | 4 | 9 | 6.65 | .360 | 1.67 | 9.7 | 5.5 | 9.3 | 67.2 | 72 | 51 | 50 | 10 | 41 | 69 | 0 | 2 | 3 | 0 | 0 | 1 | 6 | 4.76 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 39 | 57 | 0 | 4 | 2 | 4.91 | .344 | 1.58 | 9.3 | 4.9 | 8.7 | 66.0 | 68 | 39 | 36 | 5 | 36 | 64 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 3.68 |