| SP | Buehler, W.Buehler, Walker # >> | 23 | 2018 | R | 84 | 33 | 33 | 11 | 15 | 4.44 | .320 | 1.38 | 9.1 | 3.4 | 10.2 | 188.2 | 191 | 93 | 93 | 32 | 70 | 213 | 0 | 0 | 0 | 0 | 12 | 5 | 8 | 4.14 |
| SP | Millwood, K.Millwood, Kevin # >> | 25 | 1999 | R | 70 | 32 | 32 | 9 | 18 | 7.21 | .363 | 1.69 | 11.5 | 3.7 | 7.3 | 167.1 | 214 | 136 | 134 | 34 | 69 | 136 | 0 | 0 | 0 | 0 | 7 | 3 | 6 | 5.31 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 64 | 32 | 32 | 8 | 16 | 5.02 | .340 | 1.53 | 9.9 | 3.9 | 7.4 | 200.2 | 221 | 116 | 112 | 23 | 87 | 165 | 2 | 0 | 0 | 1 | 13 | 2 | 0 | 4.18 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 59 | 30 | 30 | 9 | 14 | 5.73 | .339 | 1.51 | 10.8 | 2.8 | 6.6 | 193.1 | 232 | 130 | 123 | 37 | 59 | 142 | 4 | 0 | 0 | 1 | 11 | 7 | 6 | 5.05 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 88 | 0 | 4 | 4 | 2.97 | .271 | 1.09 | 6.2 | 3.6 | 11.5 | 124.1 | 85 | 46 | 41 | 16 | 50 | 158 | 0 | 9 | 0 | 0 | 0 | 4 | 9 | 3.44 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 85 | 81 | 0 | 3 | 2 | 2.57 | .248 | 0.98 | 7.3 | 1.5 | 9.8 | 119.0 | 97 | 34 | 34 | 9 | 20 | 129 | 0 | 7 | 1 | 0 | 0 | 1 | 0 | 2.34 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 73 | 0 | 4 | 1 | 3.13 | .292 | 1.24 | 7.4 | 3.8 | 12.0 | 83.1 | 68 | 31 | 29 | 12 | 35 | 111 | 0 | 6 | 1 | 0 | 0 | 0 | 5 | 3.47 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 62 | 56 | 0 | 3 | 1 | 2.76 | .292 | 1.21 | 6.2 | 4.7 | 7.5 | 65.1 | 45 | 24 | 20 | 6 | 34 | 54 | 0 | 7 | 0 | 0 | 0 | 2 | 1 | 4.20 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 55 | 44 | 0 | 3 | 1 | 5.63 | .351 | 1.60 | 10.7 | 3.8 | 10.1 | 48.0 | 57 | 32 | 30 | 10 | 20 | 54 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.77 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 2 | 1 | 0 | 1 | 6.75 | .304 | 1.31 | 9.0 | 3.6 | 9.9 | 10.2 | 10 | 8 | 8 | 3 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.90 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 49 | 20 | 0 | 3 | 5 | 5.17 | .329 | 1.47 | 9.3 | 4.1 | 5.5 | 31.1 | 32 | 18 | 18 | 1 | 14 | 19 | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 3.55 |