| SP | Kershaw, C.Kershaw, Clayton † # >> | 28 | 2016 | L | 98 | 26 | 26 | 15 | 8 | 2.98 | .252 | 1.00 | 7.2 | 1.8 | 9.2 | 208.1 | 167 | 70 | 69 | 20 | 41 | 213 | 9 | 0 | 0 | 1 | 19 | 3 | 3 | 2.84 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 88 | 25 | 25 | 9 | 7 | 4.79 | .299 | 1.26 | 8.4 | 2.9 | 6.5 | 135.1 | 126 | 73 | 72 | 20 | 44 | 98 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 4.52 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 25 | 25 | 9 | 11 | 4.23 | .304 | 1.30 | 8.8 | 2.9 | 8.4 | 157.1 | 154 | 81 | 74 | 18 | 50 | 146 | 0 | 0 | 0 | 0 | 12 | 2 | 5 | 3.62 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 25 | 25 | 7 | 13 | 6.07 | .334 | 1.46 | 10.3 | 2.9 | 7.0 | 149.2 | 171 | 101 | 101 | 30 | 48 | 116 | 1 | 0 | 0 | 0 | 8 | 6 | 3 | 5.15 |
| SP | Brown, K.Brown, Kevin # >> | 31 | 1996 | R | 67 | 25 | 25 | 9 | 10 | 4.91 | .328 | 1.42 | 9.9 | 2.9 | 5.8 | 181.1 | 199 | 108 | 99 | 29 | 59 | 117 | 5 | 0 | 0 | 0 | 11 | 8 | 5 | 4.90 |
| RP | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 66 | 0 | 8 | 1 | 2.61 | .227 | 0.87 | 6.3 | 1.6 | 9.8 | 96.2 | 67 | 28 | 28 | 13 | 17 | 105 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 3.14 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 87 | 59 | 0 | 4 | 4 | 3.52 | .274 | 1.07 | 6.7 | 3.0 | 8.6 | 71.2 | 53 | 31 | 28 | 10 | 24 | 68 | 0 | 8 | 2 | 0 | 0 | 4 | 2 | 4.10 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 42 | 0 | 4 | 3 | 3.09 | .286 | 1.20 | 7.6 | 3.3 | 10.0 | 46.2 | 39 | 17 | 16 | 6 | 17 | 51 | 0 | 6 | 0 | 0 | 0 | 0 | 5 | 3.59 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 31 | 0 | 2 | 1 | 3.51 | .281 | 1.14 | 6.3 | 4.1 | 7.6 | 33.1 | 23 | 14 | 13 | 3 | 15 | 28 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.94 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 57 | 28 | 0 | 0 | 0 | 1.87 | .279 | 1.13 | 6.3 | 4.1 | 9.0 | 33.2 | 23 | 8 | 7 | 4 | 15 | 33 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.03 |