| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 31 | 31 | 12 | 9 | 4.19 | .297 | 1.25 | 8.9 | 2.4 | 7.3 | 210.1 | 207 | 107 | 98 | 26 | 56 | 170 | 4 | 0 | 0 | 0 | 19 | 4 | 2 | 3.85 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 30 | 30 | 11 | 13 | 4.28 | .341 | 1.52 | 11.1 | 2.6 | 5.2 | 210.1 | 259 | 107 | 100 | 17 | 60 | 121 | 3 | 0 | 0 | 0 | 15 | 7 | 5 | 3.86 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 63 | 28 | 28 | 9 | 10 | 5.46 | .342 | 1.55 | 11.0 | 2.9 | 4.8 | 181.1 | 222 | 124 | 110 | 21 | 59 | 97 | 2 | 0 | 0 | 0 | 10 | 2 | 3 | 4.45 |
| SP | Fernandez, S.Fernandez, Sid † >> | 23 | 1985 | L | 49 | 28 | 28 | 15 | 9 | 3.01 | .304 | 1.28 | 7.3 | 4.2 | 8.4 | 191.1 | 154 | 68 | 64 | 14 | 90 | 178 | 2 | 0 | 0 | 1 | 19 | 7 | 3 | 3.61 |
| SU | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 63 | 0 | 3 | 5 | 5.79 | .338 | 1.52 | 9.6 | 4.2 | 9.3 | 60.2 | 64 | 39 | 39 | 9 | 28 | 62 | 0 | 2 | 9 | 0 | 0 | 1 | 6 | 4.33 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 72 | 0 | 5 | 3 | 4.72 | .330 | 1.44 | 8.3 | 4.7 | 8.8 | 76.1 | 70 | 41 | 40 | 8 | 40 | 74 | 0 | 2 | 3 | 0 | 0 | 3 | 0 | 4.12 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 61 | 0 | 6 | 4 | 6.43 | .346 | 1.57 | 10.0 | 4.2 | 10.3 | 56.0 | 62 | 48 | 40 | 8 | 26 | 64 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 4.02 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 32 | 0 | 0 | 1 | 4.84 | .329 | 1.47 | 9.0 | 4.4 | 6.7 | 35.1 | 35 | 20 | 19 | 5 | 17 | 26 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.83 |