| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 93 | 15 | 15 | 10 | 3 | 3.52 | .276 | 1.15 | 7.9 | 2.4 | 6.3 | 110.0 | 97 | 44 | 43 | 9 | 29 | 77 | 3 | 0 | 0 | 1 | 10 | 0 | 2 | 3.45 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 16 | 16 | 7 | 4 | 1.97 | .263 | 1.06 | 6.3 | 3.3 | 9.0 | 96.0 | 67 | 23 | 21 | 7 | 35 | 96 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 3.07 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 15 | 15 | 13 | 2 | 2.51 | .252 | 1.00 | 7.6 | 1.4 | 5.8 | 111.0 | 94 | 31 | 31 | 10 | 17 | 72 | 2 | 0 | 0 | 0 | 12 | 1 | 1 | 3.36 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 15 | 15 | 6 | 5 | 4.89 | .314 | 1.35 | 9.5 | 2.7 | 4.9 | 84.2 | 89 | 48 | 46 | 14 | 25 | 46 | 3 | 0 | 0 | 1 | 8 | 2 | 2 | 5.04 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 38 | 0 | 2 | 1 | 3.31 | .291 | 1.21 | 7.5 | 3.5 | 9.8 | 54.1 | 45 | 20 | 20 | 6 | 21 | 59 | 0 | 5 | 2 | 0 | 0 | 1 | 2 | 3.48 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 35 | 0 | 1 | 0 | 5.40 | .330 | 1.48 | 8.8 | 4.5 | 9.2 | 40.0 | 39 | 24 | 24 | 5 | 20 | 41 | 0 | 9 | 2 | 0 | 0 | 0 | 0 | 4.08 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 24 | 0 | 1 | 2 | 5.88 | .297 | 1.27 | 6.9 | 4.5 | 9.3 | 26.0 | 20 | 17 | 17 | 1 | 13 | 27 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 2.92 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 9 | 0 | 2 | 1 | 4.09 | .340 | 1.55 | 11.5 | 2.5 | 6.5 | 11.0 | 14 | 5 | 5 | 2 | 3 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.73 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 14 | 0 | 0 | 2 | 5.19 | .297 | 1.27 | 7.9 | 3.7 | 8.5 | 17.1 | 15 | 10 | 10 | 5 | 7 | 16 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 6.18 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 8 | 0 | 1 | 0 | 5.16 | .288 | 1.21 | 8.4 | 2.8 | 8.1 | 29.2 | 27 | 20 | 17 | 5 | 9 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.38 |