| SP | Gallen, Z.Gallen, Zac # >> | 26 | 2022 | R | 94 | 18 | 18 | 7 | 8 | 3.57 | .307 | 1.33 | 8.5 | 3.4 | 8.8 | 116.0 | 110 | 51 | 46 | 16 | 44 | 113 | 0 | 0 | 0 | 0 | 12 | 0 | 1 | 3.98 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 91 | 18 | 18 | 6 | 8 | 5.54 | .341 | 1.53 | 10.7 | 3.1 | 8.7 | 115.1 | 137 | 77 | 71 | 16 | 40 | 111 | 1 | 0 | 0 | 0 | 10 | 2 | 2 | 3.97 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 78 | 18 | 18 | 8 | 4 | 3.94 | .330 | 1.42 | 9.7 | 3.1 | 8.4 | 105.0 | 113 | 53 | 46 | 9 | 36 | 98 | 0 | 0 | 0 | 0 | 10 | 6 | 1 | 3.45 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 75 | 17 | 17 | 6 | 7 | 5.66 | .325 | 1.39 | 10.2 | 2.3 | 8.5 | 97.0 | 110 | 65 | 61 | 14 | 25 | 92 | 0 | 0 | 0 | 0 | 6 | 5 | 0 | 3.91 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 43 | 0 | 4 | 1 | 2.68 | .233 | 0.89 | 5.8 | 2.2 | 8.1 | 57.0 | 37 | 20 | 17 | 3 | 14 | 51 | 0 | 5 | 3 | 0 | 0 | 1 | 0 | 2.68 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 43 | 0 | 3 | 2 | 3.28 | .308 | 1.32 | 8.4 | 3.5 | 10.3 | 49.1 | 46 | 20 | 18 | 8 | 19 | 56 | 0 | 9 | 1 | 0 | 0 | 1 | 0 | 4.06 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 22 | 0 | 2 | 2 | 4.20 | .244 | 0.97 | 7.5 | 1.2 | 9.3 | 30.0 | 25 | 14 | 14 | 6 | 4 | 31 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.93 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 25 | 0 | 1 | 0 | 3.81 | .257 | 1.00 | 6.6 | 2.4 | 7.3 | 26.0 | 19 | 15 | 11 | 7 | 7 | 21 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 5.81 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 59 | 7 | 0 | 0 | 1 | 4.20 | .262 | 1.07 | 6.6 | 3.0 | 11.4 | 15.0 | 11 | 7 | 7 | 1 | 5 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.33 |