| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 92 | 34 | 34 | 9 | 19 | 5.10 | .333 | 1.47 | 9.3 | 3.9 | 9.0 | 201.1 | 208 | 120 | 114 | 23 | 88 | 201 | 1 | 0 | 0 | 0 | 17 | 6 | 5 | 3.89 |
| SP | Maine, J.Maine, John # >> | 25 | 2006 | R | 69 | 34 | 34 | 4 | 17 | 5.39 | .337 | 1.51 | 9.9 | 3.7 | 6.4 | 173.2 | 190 | 106 | 104 | 35 | 72 | 123 | 0 | 0 | 0 | 0 | 15 | 3 | 1 | 5.51 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 66 | 32 | 32 | 2 | 14 | 7.13 | .382 | 1.81 | 12.0 | 4.4 | 5.6 | 152.2 | 202 | 122 | 121 | 22 | 75 | 95 | 0 | 0 | 0 | 0 | 10 | 6 | 6 | 5.23 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 52 | 31 | 31 | 8 | 18 | 5.63 | .346 | 1.56 | 11.0 | 3.1 | 7.0 | 174.1 | 213 | 113 | 109 | 31 | 59 | 136 | 1 | 0 | 0 | 0 | 12 | 5 | 9 | 4.86 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 46 | 31 | 31 | 9 | 13 | 5.63 | .360 | 1.67 | 10.4 | 4.7 | 7.4 | 150.1 | 173 | 101 | 94 | 21 | 78 | 124 | 0 | 0 | 0 | 0 | 13 | 3 | 4 | 4.79 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 95 | 0 | 3 | 3 | 3.47 | .265 | 1.06 | 6.2 | 3.3 | 10.3 | 111.2 | 77 | 43 | 43 | 12 | 41 | 127 | 0 | 9 | 2 | 0 | 0 | 3 | 3 | 3.31 |
| RP | Mota, G.Mota, Guillermo † >> | 30 | 2003 | R | 49 | 85 | 0 | 7 | 6 | 3.15 | .290 | 1.16 | 8.3 | 2.2 | 6.3 | 123.0 | 113 | 46 | 43 | 11 | 30 | 86 | 0 | 3 | 1 | 0 | 0 | 8 | 0 | 3.69 |
| RP | Turnbow, D.Turnbow, Derrick >> | 27 | 2005 | R | 34 | 71 | 0 | 1 | 5 | 4.89 | .342 | 1.52 | 7.8 | 6.0 | 6.8 | 84.2 | 73 | 49 | 46 | 10 | 56 | 63 | 0 | 5 | 2 | 0 | 0 | 3 | 8 | 5.15 |
| RP | Farnsworth, K.Farnsworth, Kyle >> | 25 | 2001 | R | 22 | 70 | 0 | 5 | 6 | 5.23 | .334 | 1.47 | 7.6 | 5.8 | 9.7 | 75.2 | 63 | 46 | 44 | 10 | 48 | 81 | 0 | 2 | 3 | 0 | 0 | 3 | 4 | 4.61 |
| SP | Patterson, J.Patterson, John >> | 27 | 2005 | R | 32 | 49 | 0 | 5 | 5 | 6.48 | .373 | 1.75 | 10.4 | 5.4 | 5.2 | 83.1 | 96 | 60 | 60 | 17 | 50 | 48 | 0 | 6 | 0 | 0 | 0 | 3 | 5 | 6.42 |