| SP | Harden, R.Harden, Rich † >> | 27 | 2008 | R | 95 | 36 | 36 | 17 | 5 | 3.25 | .298 | 1.24 | 7.2 | 4.0 | 8.6 | 227.0 | 182 | 88 | 82 | 20 | 100 | 217 | 0 | 0 | 0 | 0 | 25 | 7 | 2 | 3.65 |
| SP | Perez, O.Perez, Oliver # >> | 23 | 2004 | L | 75 | 34 | 33 | 9 | 11 | 5.33 | .331 | 1.44 | 8.2 | 4.8 | 9.1 | 201.0 | 183 | 121 | 119 | 30 | 107 | 203 | 3 | 0 | 0 | 1 | 17 | 8 | 1 | 4.64 |
| SP | Moyer, J.Moyer, Jamie # >> | 40 | 2002 | L | 61 | 34 | 33 | 11 | 10 | 5.77 | .334 | 1.48 | 10.3 | 3.1 | 6.4 | 179.1 | 205 | 121 | 115 | 41 | 61 | 127 | 0 | 0 | 0 | 0 | 12 | 4 | 0 | 5.65 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 54 | 33 | 33 | 7 | 14 | 6.08 | .370 | 1.73 | 11.8 | 3.8 | 7.3 | 191.0 | 250 | 137 | 129 | 30 | 81 | 154 | 1 | 0 | 0 | 0 | 12 | 6 | 5 | 4.80 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 49 | 31 | 31 | 14 | 9 | 5.13 | .356 | 1.64 | 10.4 | 4.5 | 5.7 | 180.2 | 207 | 109 | 103 | 31 | 89 | 113 | 0 | 0 | 0 | 0 | 12 | 4 | 6 | 5.53 |
| RP | Foulke, K.Foulke, Keith † >> | 31 | 2003 | R | 76 | 89 | 0 | 9 | 7 | 4.08 | .276 | 1.13 | 8.4 | 1.9 | 8.8 | 125.2 | 116 | 64 | 57 | 15 | 26 | 122 | 0 | 12 | 6 | 0 | 0 | 2 | 0 | 3.28 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 60 | 78 | 0 | 3 | 9 | 4.26 | .329 | 1.46 | 8.5 | 4.6 | 9.2 | 93.0 | 88 | 47 | 44 | 13 | 48 | 95 | 0 | 9 | 4 | 0 | 0 | 1 | 3 | 4.35 |
| RP | Linebrink, S.Linebrink, Scott >> | 28 | 2004 | R | 44 | 65 | 0 | 6 | 7 | 4.22 | .282 | 1.17 | 7.5 | 3.0 | 8.4 | 74.2 | 62 | 35 | 35 | 15 | 25 | 69 | 0 | 13 | 1 | 0 | 0 | 1 | 3 | 4.82 |
| RP | Fuentes, B.Fuentes, Brian >> | 33 | 2008 | L | 31 | 44 | 0 | 3 | 1 | 4.27 | .339 | 1.50 | 9.2 | 4.5 | 9.7 | 52.2 | 53 | 25 | 25 | 9 | 26 | 56 | 0 | 3 | 1 | 0 | 0 | 2 | 3 | 4.71 |