| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 36 | 36 | 8 | 9 | 3.85 | .315 | 1.38 | 8.8 | 3.6 | 9.8 | 159.0 | 156 | 76 | 68 | 19 | 63 | 174 | 0 | 0 | 0 | 0 | 1 | 0 | 4 | 3.55 |
| SP | Sabathia, C.Sabathia, CC # >> | 28 | 2008 | L | 60 | 33 | 33 | 16 | 13 | 4.80 | .313 | 1.33 | 9.4 | 2.5 | 7.8 | 234.1 | 245 | 134 | 125 | 31 | 66 | 203 | 7 | 0 | 0 | 1 | 17 | 9 | 6 | 3.95 |
| SP | Burnett, A.Burnett, A.J. # >> | 25 | 2002 | R | 56 | 33 | 33 | 12 | 13 | 5.33 | .345 | 1.54 | 8.8 | 5.1 | 8.3 | 206.0 | 201 | 123 | 122 | 26 | 117 | 190 | 0 | 0 | 0 | 0 | 13 | 7 | 11 | 4.60 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 89 | 0 | 7 | 2 | 2.79 | .246 | 0.95 | 6.8 | 1.8 | 9.1 | 142.0 | 107 | 45 | 44 | 14 | 28 | 143 | 0 | 6 | 3 | 0 | 0 | 4 | 2 | 2.94 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 84 | 0 | 4 | 3 | 3.73 | .278 | 1.14 | 6.6 | 3.6 | 9.6 | 111.0 | 82 | 49 | 46 | 11 | 44 | 119 | 0 | 12 | 2 | 0 | 0 | 2 | 5 | 3.39 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 63 | 67 | 0 | 5 | 4 | 3.67 | .282 | 1.15 | 7.9 | 2.5 | 7.8 | 90.2 | 79 | 38 | 37 | 8 | 25 | 78 | 0 | 8 | 5 | 0 | 0 | 3 | 7 | 3.36 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 48 | 61 | 0 | 7 | 1 | 3.27 | .274 | 1.09 | 7.0 | 2.8 | 5.8 | 77.0 | 60 | 28 | 28 | 12 | 24 | 50 | 0 | 5 | 2 | 0 | 0 | 3 | 0 | 4.78 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 37 | 52 | 0 | 4 | 3 | 3.30 | .329 | 1.40 | 7.4 | 5.4 | 8.1 | 62.2 | 51 | 25 | 23 | 4 | 37 | 56 | 0 | 5 | 2 | 0 | 0 | 4 | 1 | 4.02 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 45 | 29 | 0 | 4 | 9 | 6.52 | .355 | 1.63 | 10.5 | 4.4 | 7.0 | 49.2 | 57 | 39 | 36 | 7 | 24 | 38 | 0 | 6 | 2 | 0 | 0 | 1 | 1 | 4.84 |