| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 33 | 33 | 16 | 12 | 3.23 | .260 | 1.04 | 6.9 | 2.4 | 9.6 | 223.0 | 172 | 83 | 80 | 21 | 59 | 239 | 8 | 0 | 0 | 3 | 22 | 4 | 4 | 2.93 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 86 | 34 | 34 | 12 | 14 | 3.97 | .303 | 1.26 | 8.9 | 2.5 | 6.9 | 240.1 | 237 | 111 | 106 | 25 | 66 | 183 | 8 | 0 | 0 | 2 | 20 | 11 | 6 | 3.79 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 80 | 32 | 32 | 16 | 8 | 4.44 | .326 | 1.43 | 8.7 | 4.3 | 10.0 | 198.2 | 191 | 99 | 98 | 28 | 94 | 219 | 1 | 0 | 0 | 0 | 17 | 3 | 3 | 4.10 |
| SP | Pettitte, A.Pettitte, Andy # >> | 33 | 2005 | L | 77 | 32 | 32 | 13 | 8 | 3.91 | .301 | 1.27 | 8.9 | 2.5 | 5.6 | 202.1 | 199 | 94 | 88 | 24 | 57 | 126 | 2 | 0 | 0 | 1 | 19 | 6 | 5 | 4.23 |
| CL | Saito, T.Saito, Takashi † >> | 37 | 2007 | R | 100 | 65 | 0 | 6 | 6 | 3.00 | .266 | 1.04 | 6.7 | 2.7 | 10.6 | 69.0 | 51 | 23 | 23 | 6 | 21 | 81 | 0 | 42 | 3 | 0 | 0 | 3 | 0 | 2.83 |
| SU | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 86 | 43 | 0 | 1 | 4 | 3.84 | .272 | 1.09 | 6.0 | 3.9 | 6.4 | 63.1 | 42 | 28 | 27 | 4 | 27 | 45 | 0 | 0 | 9 | 0 | 0 | 2 | 1 | 3.78 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 86 | 82 | 0 | 4 | 3 | 3.09 | .258 | 1.02 | 5.7 | 3.5 | 9.7 | 96.0 | 61 | 33 | 33 | 11 | 37 | 103 | 0 | 4 | 4 | 0 | 0 | 2 | 4 | 3.56 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 82 | 58 | 0 | 5 | 4 | 2.67 | .295 | 1.24 | 7.7 | 3.5 | 9.5 | 57.1 | 49 | 17 | 17 | 7 | 22 | 60 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 3.70 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 72 | 30 | 0 | 4 | 1 | 1.91 | .346 | 1.55 | 8.0 | 6.1 | 6.1 | 28.1 | 25 | 6 | 6 | 1 | 19 | 19 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.25 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 69 | 31 | 0 | 4 | 0 | 3.84 | .323 | 1.42 | 8.4 | 4.4 | 10.0 | 65.2 | 61 | 31 | 28 | 4 | 32 | 72 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 3.11 |