| SP | Eovaldi, N.Eovaldi, Nathan >> | 35 | 2025 | R | 99 | 21 | 21 | 6 | 6 | 3.57 | .283 | 1.17 | 8.4 | 2.2 | 7.2 | 133.2 | 124 | 55 | 53 | 12 | 32 | 107 | 1 | 0 | 0 | 0 | 11 | 2 | 5 | 3.33 |
| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 90 | 22 | 21 | 11 | 5 | 4.56 | .311 | 1.34 | 8.6 | 3.6 | 8.3 | 124.1 | 118 | 65 | 63 | 21 | 49 | 115 | 0 | 0 | 0 | 0 | 10 | 1 | 2 | 4.56 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 72 | 21 | 20 | 11 | 6 | 4.75 | .346 | 1.55 | 9.2 | 4.8 | 9.3 | 130.2 | 133 | 71 | 69 | 16 | 69 | 134 | 0 | 0 | 0 | 0 | 13 | 5 | 4 | 4.25 |
| SP | Cheney, T.Cheney, Tom # >> | 29 | 1963 | R | 66 | 19 | 19 | 9 | 6 | 3.84 | .280 | 1.16 | 7.7 | 2.7 | 6.0 | 122.0 | 105 | 52 | 52 | 17 | 36 | 82 | 1 | 0 | 0 | 1 | 10 | 1 | 0 | 4.38 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 100 | 59 | 0 | 9 | 3 | 2.06 | .266 | 1.07 | 5.7 | 3.9 | 9.9 | 96.1 | 61 | 22 | 22 | 4 | 42 | 106 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 2.71 |
| RP | Uehara, K.Uehara, Koji >> | 37 | 2012 | R | 94 | 52 | 0 | 5 | 2 | 3.39 | .288 | 1.16 | 8.4 | 2.1 | 9.7 | 61.0 | 57 | 24 | 23 | 12 | 14 | 66 | 0 | 4 | 1 | 0 | 0 | 3 | 0 | 4.23 |
| RP | Leclerc, J.Leclerc, Jose >> | 24 | 2018 | R | 89 | 37 | 0 | 3 | 3 | 3.50 | .294 | 1.22 | 5.3 | 5.8 | 10.3 | 36.0 | 21 | 16 | 14 | 1 | 23 | 41 | 0 | 7 | 0 | 0 | 0 | 1 | 3 | 3.08 |
| RP | Armstrong, S.Armstrong, Shawn >> | 34 | 2025 | R | 82 | 19 | 0 | 3 | 0 | 0.96 | .253 | 1.02 | 7.0 | 2.5 | 6.0 | 18.2 | 14 | 2 | 2 | 1 | 5 | 12 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.22 |
| RP | Soria, J.Soria, Joakim >> | 30 | 2014 | R | 57 | 21 | 0 | 1 | 0 | 3.04 | .238 | 0.94 | 7.6 | 1.0 | 10.0 | 26.2 | 22 | 9 | 9 | 2 | 3 | 29 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.12 |
| SP | Scherzer, M.Scherzer, Max >> | 39 | 2023 | R | 96 | 16 | 2 | 1 | 0 | 4.07 | .296 | 1.24 | 7.9 | 3.2 | 7.5 | 42.0 | 37 | 20 | 19 | 6 | 15 | 35 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.33 |