| SP | Eovaldi, N.Eovaldi, Nathan >> | 35 | 2025 | R | 97 | 9 | 9 | 3 | 3 | 3.49 | .279 | 1.15 | 7.5 | 2.9 | 5.5 | 59.1 | 49 | 25 | 23 | 5 | 19 | 36 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 3.90 |
| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 79 | 9 | 9 | 1 | 4 | 7.99 | .356 | 1.66 | 12.3 | 2.9 | 8.1 | 41.2 | 56 | 38 | 37 | 12 | 13 | 37 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 5.95 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 70 | 8 | 8 | 3 | 4 | 3.93 | .332 | 1.49 | 8.1 | 5.4 | 10.4 | 50.1 | 45 | 25 | 22 | 6 | 30 | 58 | 1 | 0 | 0 | 0 | 4 | 0 | 3 | 4.04 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 98 | 25 | 0 | 3 | 0 | 2.01 | .219 | 0.84 | 5.0 | 2.7 | 8.8 | 40.1 | 22 | 9 | 9 | 2 | 12 | 39 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.60 |
| RP | Uehara, K.Uehara, Koji >> | 37 | 2012 | R | 92 | 19 | 0 | 2 | 1 | 2.70 | .300 | 1.29 | 9.0 | 2.7 | 9.0 | 23.1 | 23 | 7 | 7 | 1 | 7 | 23 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 2.48 |
| RP | Leclerc, J.Leclerc, Jose >> | 24 | 2018 | R | 90 | 12 | 0 | 4 | 1 | 1.15 | .161 | 0.57 | 3.0 | 2.4 | 8.4 | 15.2 | 5 | 2 | 2 | 1 | 4 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.80 |
| RP | Armstrong, S.Armstrong, Shawn >> | 34 | 2025 | R | 86 | 10 | 0 | 2 | 0 | 2.08 | .188 | 0.69 | 4.5 | 2.3 | 6.8 | 8.2 | 4 | 2 | 2 | 0 | 2 | 6 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.25 |
| RP | Soria, J.Soria, Joakim >> | 30 | 2014 | R | 65 | 7 | 0 | 0 | 0 | 1.93 | .263 | 0.96 | 8.0 | 1.0 | 12.0 | 9.1 | 8 | 2 | 2 | 0 | 1 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1.00 |
| SP | Scherzer, M.Scherzer, Max >> | 39 | 2023 | R | 91 | 7 | 0 | 0 | 1 | 5.71 | .358 | 1.67 | 10.6 | 4.8 | 6.4 | 17.1 | 20 | 11 | 11 | 2 | 9 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.71 |