| SP | Wacha, M.Wacha, Michael >> | 32 | 2015 | R | 83 | 14 | 14 | 3 | 7 | 4.80 | .304 | 1.30 | 8.9 | 2.8 | 8.2 | 86.1 | 85 | 46 | 46 | 13 | 27 | 78 | 2 | 0 | 0 | 0 | 7 | 1 | 0 | 4.13 |
| SP | Doubront, F.Doubront, Felix >> | 30 | 2012 | L | 53 | 14 | 14 | 1 | 8 | 5.93 | .312 | 1.35 | 8.9 | 3.3 | 8.6 | 71.1 | 70 | 48 | 47 | 17 | 26 | 68 | 1 | 0 | 0 | 0 | 6 | 1 | 1 | 5.34 |
| SP | Wakefield, T.Wakefield, Tim # >> | 44 | 2008 | R | 40 | 13 | 13 | 5 | 5 | 3.41 | .291 | 1.23 | 8.0 | 3.0 | 6.6 | 74.0 | 66 | 28 | 28 | 11 | 25 | 54 | 0 | 0 | 0 | 0 | 6 | 0 | 2 | 4.49 |
| RP | Delcarmen, M.Delcarmen, Manny >> | 28 | 2008 | R | 80 | 33 | 0 | 5 | 3 | 2.77 | .343 | 1.56 | 10.6 | 3.5 | 8.3 | 39.0 | 46 | 12 | 12 | 3 | 15 | 36 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.31 |
| RP | Mortensen, C.Mortensen, Clayton >> | 33 | 2012 | R | 64 | 22 | 0 | 1 | 2 | 4.50 | .268 | 1.10 | 6.8 | 3.2 | 11.3 | 20.0 | 15 | 10 | 10 | 3 | 7 | 25 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 3.50 |
| RP | Ramirez, R.Ramirez, Ramon >> | 29 | 2008 | R | 60 | 8 | 0 | 0 | 0 | 3.18 | .292 | 1.24 | 8.2 | 3.3 | 5.7 | 11.1 | 10 | 4 | 4 | 0 | 4 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2.82 |
| CL | Uehara, K.Uehara, Koji >> | 41 | 2011 | R | 60 | 26 | 0 | 1 | 0 | 4.30 | .281 | 1.09 | 5.5 | 4.3 | 7.4 | 23.0 | 14 | 11 | 11 | 3 | 11 | 19 | 0 | 15 | 2 | 0 | 0 | 2 | 0 | 4.74 |
| RP | Wheeler, D.Wheeler, Dan >> | 35 | 2009 | R | 55 | 8 | 0 | 0 | 0 | 0.96 | .263 | 0.96 | 7.0 | 2.0 | 5.0 | 9.1 | 7 | 1 | 1 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.89 |
| SP | Gabbard, K.Gabbard, Kason >> | 26 | 2007 | L | 57 | 14 | 0 | 3 | 3 | 5.11 | .371 | 1.77 | 8.4 | 7.6 | 8.6 | 44.0 | 41 | 25 | 25 | 6 | 37 | 42 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 5.39 |