| SP | Wacha, M.Wacha, Michael >> | 30 | 2015 | R | 79 | 23 | 23 | 6 | 12 | 3.91 | .292 | 1.21 | 8.8 | 2.1 | 6.6 | 156.1 | 152 | 76 | 68 | 17 | 37 | 115 | 2 | 0 | 0 | 0 | 13 | 4 | 1 | 3.73 |
| SP | Doubront, F.Doubront, Felix >> | 28 | 2012 | L | 53 | 23 | 23 | 8 | 9 | 3.20 | .295 | 1.21 | 7.1 | 3.8 | 9.4 | 143.1 | 113 | 59 | 51 | 24 | 61 | 149 | 0 | 0 | 0 | 0 | 16 | 6 | 4 | 4.50 |
| SP | Wakefield, T.Wakefield, Tim # >> | 42 | 2008 | R | 50 | 23 | 23 | 4 | 10 | 4.91 | .326 | 1.42 | 9.0 | 3.8 | 6.2 | 128.1 | 128 | 71 | 70 | 13 | 54 | 88 | 0 | 0 | 0 | 0 | 12 | 4 | 6 | 4.30 |
| CL | Uehara, K.Uehara, Koji >> | 39 | 2011 | R | 76 | 35 | 0 | 0 | 2 | 4.18 | .297 | 1.24 | 7.6 | 3.7 | 9.3 | 32.1 | 27 | 15 | 15 | 3 | 13 | 33 | 0 | 22 | 4 | 0 | 0 | 1 | 0 | 3.47 |
| RP | Mortensen, C.Mortensen, Clayton >> | 31 | 2012 | R | 67 | 53 | 0 | 4 | 8 | 3.39 | .314 | 1.37 | 8.2 | 4.2 | 9.7 | 66.1 | 60 | 29 | 25 | 5 | 31 | 71 | 0 | 4 | 1 | 0 | 0 | 0 | 5 | 3.24 |
| RP | Wheeler, D.Wheeler, Dan >> | 33 | 2009 | R | 65 | 27 | 0 | 1 | 1 | 2.48 | .250 | 1.00 | 6.8 | 2.2 | 9.9 | 29.0 | 22 | 8 | 8 | 4 | 7 | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.31 |
| RP | Delcarmen, M.Delcarmen, Manny >> | 26 | 2008 | R | 57 | 17 | 0 | 2 | 2 | 4.15 | .358 | 1.67 | 10.1 | 5.3 | 6.9 | 17.1 | 19 | 9 | 8 | 3 | 10 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.53 |
| RP | Aceves, A.Aceves, Alfredo # >> | 32 | 2011 | R | 54 | 19 | 0 | 0 | 0 | 5.28 | .341 | 1.45 | 7.1 | 5.9 | 4.0 | 29.0 | 23 | 17 | 17 | 7 | 19 | 13 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 7.52 |
| SP | Matsuzaka, D.Matsuzaka, Daisuke >> | 28 | 2008 | R | 50 | 19 | 0 | 3 | 3 | 3.92 | .329 | 1.46 | 7.1 | 6.0 | 7.6 | 85.0 | 67 | 39 | 37 | 9 | 57 | 72 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 4.73 |