| SP | Hamels, C.Hamels, Cole # >> | 36 | 2011 | L | 74 | 26 | 26 | 6 | 13 | 5.18 | .308 | 1.27 | 9.4 | 2.1 | 6.0 | 153.0 | 159 | 96 | 88 | 27 | 36 | 102 | 1 | 0 | 0 | 1 | 11 | 9 | 1 | 4.84 |
| SP | Zambrano, C.Zambrano, Carlos >> | 26 | 2005 | R | 83 | 21 | 15 | 7 | 8 | 4.08 | .296 | 1.22 | 7.4 | 3.6 | 7.1 | 130.0 | 107 | 63 | 59 | 13 | 52 | 102 | 3 | 1 | 0 | 0 | 9 | 5 | 3 | 4.05 |
| SP | Hendricks, K.Hendricks, Kyle >> | 39 | 2016 | R | 59 | 26 | 26 | 9 | 10 | 4.11 | .319 | 1.39 | 9.6 | 2.9 | 7.7 | 153.1 | 163 | 81 | 70 | 15 | 50 | 131 | 0 | 0 | 0 | 0 | 12 | 2 | 4 | 3.58 |
| RP | Givens, M.Givens, Mychal >> | 37 | 2015 | R | 39 | 67 | 0 | 4 | 2 | 2.81 | .296 | 1.26 | 7.9 | 3.6 | 6.4 | 73.2 | 64 | 23 | 23 | 3 | 29 | 52 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.30 |
| RP | Guzman, A.Guzman, Angel >> | 34 | 2009 | R | 53 | 55 | 0 | 2 | 1 | 2.55 | .309 | 1.30 | 8.5 | 3.2 | 5.3 | 53.0 | 50 | 16 | 15 | 5 | 19 | 31 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 4.25 |
| SU | Borowski, J.Borowski, Joe >> | 32 | 2003 | R | 61 | 55 | 0 | 3 | 3 | 2.19 | .269 | 1.07 | 5.6 | 4.1 | 7.1 | 53.1 | 33 | 13 | 13 | 4 | 24 | 42 | 0 | 2 | 4 | 0 | 0 | 2 | 0 | 3.87 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2014 | L | 80 | 56 | 0 | 3 | 3 | 2.45 | .239 | 0.92 | 5.2 | 3.3 | 8.0 | 47.2 | 27 | 14 | 13 | 3 | 17 | 42 | 0 | 21 | 1 | 0 | 0 | 1 | 3 | 3.19 |