| SP | Liriano, F.Liriano, Francisco >> | 26 | 2006 | L | 100 | 26 | 26 | 10 | 8 | 2.76 | .246 | 0.95 | 6.9 | 1.6 | 9.3 | 153.1 | 118 | 51 | 47 | 20 | 27 | 158 | 0 | 0 | 0 | 0 | 12 | 5 | 3 | 3.26 |
| SP | Alvarez, H.Alvarez, Henderson >> | 29 | 2011 | R | 95 | 26 | 26 | 12 | 9 | 4.20 | .290 | 1.19 | 8.5 | 2.2 | 6.8 | 173.2 | 163 | 86 | 81 | 28 | 43 | 130 | 3 | 0 | 0 | 1 | 13 | 7 | 4 | 4.47 |
| SP | Sanchez, A.Sanchez, Aaron >> | 36 | 2016 | R | 77 | 26 | 26 | 12 | 8 | 4.33 | .306 | 1.29 | 8.9 | 2.7 | 6.7 | 172.2 | 171 | 87 | 83 | 26 | 52 | 128 | 2 | 0 | 0 | 0 | 16 | 5 | 3 | 4.47 |
| SP | McGowan, D.McGowan, Dustin >> | 29 | 2007 | R | 77 | 26 | 26 | 6 | 9 | 4.54 | .313 | 1.35 | 8.6 | 3.6 | 7.0 | 168.2 | 161 | 88 | 85 | 23 | 67 | 130 | 3 | 0 | 0 | 0 | 14 | 3 | 2 | 4.48 |
| SP | Marcum, S.Marcum, Shaun >> | 32 | 2008 | R | 76 | 25 | 25 | 6 | 13 | 4.57 | .326 | 1.41 | 8.9 | 3.8 | 6.9 | 155.2 | 153 | 89 | 79 | 24 | 66 | 119 | 1 | 0 | 0 | 1 | 12 | 7 | 2 | 4.89 |
| CL | Soria, J.Soria, Joakim >> | 29 | 2008 | R | 97 | 50 | 0 | 9 | 3 | 2.65 | .241 | 0.88 | 5.1 | 3.0 | 6.9 | 57.2 | 32 | 17 | 17 | 5 | 19 | 44 | 0 | 28 | 5 | 0 | 0 | 4 | 1 | 3.81 |
| SU | Morrow, B.Morrow, Brandon >> | 29 | 2008 | R | 96 | 46 | 0 | 0 | 0 | 2.03 | .263 | 0.99 | 6.2 | 2.8 | 9.8 | 48.2 | 33 | 12 | 11 | 2 | 15 | 52 | 0 | 9 | 0 | 0 | 0 | 4 | 3 | 2.56 |
| RP | Dotel, O.Dotel, Octavio >> | 30 | 2003 | R | 83 | 61 | 0 | 6 | 5 | 2.54 | .264 | 1.04 | 5.6 | 3.8 | 9.4 | 74.1 | 46 | 21 | 21 | 5 | 31 | 77 | 0 | 0 | 2 | 0 | 0 | 3 | 3 | 3.18 |
| RP | League, B.League, Brandon >> | 26 | 2006 | R | 83 | 51 | 0 | 5 | 4 | 3.46 | .273 | 1.10 | 8.3 | 1.6 | 6.6 | 78.0 | 72 | 33 | 30 | 13 | 14 | 57 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.32 |
| RP | Accardo, J.Accardo, Jeremy >> | 30 | 2007 | R | 74 | 34 | 0 | 0 | 1 | 4.43 | .308 | 1.31 | 8.4 | 3.6 | 6.6 | 42.2 | 39 | 22 | 21 | 5 | 17 | 31 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.36 |