| SP | Alvarez, H.Alvarez, Henderson >> | 26 | 2011 | R | 90 | 15 | 15 | 3 | 6 | 4.75 | .296 | 1.24 | 9.5 | 1.7 | 7.6 | 102.1 | 108 | 55 | 54 | 14 | 19 | 86 | 2 | 0 | 0 | 1 | 7 | 2 | 5 | 3.72 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 88 | 14 | 14 | 3 | 3 | 3.34 | .263 | 1.01 | 6.7 | 2.4 | 10.9 | 67.1 | 50 | 25 | 25 | 6 | 18 | 81 | 0 | 0 | 0 | 0 | 0 | 4 | 4 | 2.73 |
| SP | Sanchez, A.Sanchez, Aaron >> | 33 | 2016 | R | 87 | 14 | 14 | 5 | 8 | 6.38 | .309 | 1.30 | 9.5 | 2.3 | 6.3 | 79.0 | 83 | 56 | 56 | 18 | 20 | 55 | 2 | 0 | 0 | 0 | 6 | 3 | 2 | 5.44 |
| SP | Stroman, M.Stroman, Marcus >> | 31 | 2014 | R | 80 | 14 | 14 | 6 | 5 | 5.05 | .286 | 1.16 | 8.6 | 1.9 | 7.7 | 87.1 | 83 | 49 | 49 | 14 | 18 | 74 | 0 | 0 | 0 | 0 | 7 | 4 | 4 | 4.15 |
| SP | Romero, R.Romero, Ricky >> | 31 | 2011 | L | 75 | 14 | 14 | 3 | 9 | 6.05 | .356 | 1.60 | 10.8 | 3.7 | 5.4 | 86.1 | 103 | 62 | 58 | 12 | 35 | 52 | 2 | 0 | 0 | 0 | 6 | 5 | 0 | 5.00 |
| CL | Soria, J.Soria, Joakim >> | 26 | 2008 | R | 92 | 27 | 0 | 3 | 3 | 3.07 | .273 | 1.13 | 7.8 | 2.5 | 7.4 | 29.1 | 25 | 10 | 10 | 0 | 8 | 24 | 0 | 14 | 2 | 0 | 0 | 0 | 0 | 2.17 |
| RP | Rzepczynski, M.Rzepczynski, Marc >> | 30 | 2011 | L | 83 | 32 | 0 | 1 | 0 | 1.78 | .232 | 0.89 | 6.5 | 1.6 | 8.1 | 50.2 | 36 | 15 | 10 | 1 | 9 | 45 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 2.06 |
| RP | Morrow, B.Morrow, Brandon >> | 26 | 2008 | R | 82 | 24 | 0 | 3 | 2 | 3.31 | .290 | 1.22 | 7.0 | 4.2 | 9.3 | 32.2 | 25 | 12 | 12 | 4 | 15 | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.97 |
| RP | Accardo, J.Accardo, Jeremy >> | 27 | 2007 | R | 67 | 17 | 0 | 0 | 2 | 2.22 | .247 | 0.95 | 6.4 | 2.3 | 6.0 | 24.1 | 17 | 6 | 6 | 3 | 6 | 16 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.17 |
| SP | Marcum, S.Marcum, Shaun >> | 29 | 2008 | R | 70 | 16 | 0 | 6 | 0 | 4.02 | .311 | 1.32 | 9.2 | 2.7 | 5.9 | 56.0 | 57 | 26 | 25 | 9 | 17 | 37 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.79 |