| SP | Martinez, P.Martinez, Pedro >> | 32 | 2003 | R | 84 | 28 | 28 | 10 | 12 | 4.86 | .335 | 1.47 | 9.5 | 3.7 | 8.9 | 152.0 | 160 | 90 | 82 | 20 | 63 | 151 | 0 | 0 | 0 | 0 | 15 | 7 | 3 | 4.11 |
| SP | Syndergaard, N.Syndergaard, Noah >> | 36 | 2016 | R | 71 | 27 | 27 | 8 | 11 | 4.83 | .302 | 1.27 | 9.4 | 2.1 | 8.6 | 156.2 | 163 | 86 | 84 | 23 | 36 | 149 | 4 | 0 | 0 | 1 | 11 | 4 | 12 | 3.78 |
| SP | Halladay, R.Halladay, Roy # >> | 26 | 2003 | R | 62 | 27 | 27 | 10 | 11 | 4.81 | .293 | 1.22 | 8.8 | 2.2 | 6.6 | 170.1 | 167 | 94 | 91 | 25 | 41 | 124 | 4 | 0 | 0 | 1 | 10 | 4 | 3 | 4.25 |
| SP | Burnett, A.Burnett, A.J. >> | 34 | 2007 | R | 57 | 26 | 26 | 7 | 9 | 4.79 | .350 | 1.60 | 9.5 | 4.9 | 8.9 | 139.0 | 147 | 86 | 74 | 17 | 76 | 137 | 0 | 0 | 0 | 0 | 10 | 2 | 0 | 4.30 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 31 | 2007 | R | 98 | 56 | 0 | 2 | 5 | 3.53 | .311 | 1.35 | 8.6 | 3.5 | 9.2 | 51.0 | 49 | 20 | 20 | 8 | 20 | 52 | 0 | 27 | 3 | 0 | 0 | 0 | 0 | 4.18 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 75 | 81 | 0 | 8 | 2 | 3.56 | .305 | 1.28 | 7.4 | 4.2 | 8.0 | 78.1 | 64 | 33 | 31 | 6 | 36 | 69 | 0 | 1 | 2 | 0 | 0 | 3 | 0 | 3.73 |
| RP | Gordon, T.Gordon, Tom # >> | 38 | 2004 | R | 72 | 72 | 0 | 2 | 3 | 5.88 | .303 | 1.29 | 8.4 | 3.2 | 10.3 | 64.1 | 60 | 44 | 42 | 10 | 23 | 73 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 3.88 |
| RP | Urbina, U.Urbina, Ugueth >> | 33 | 2005 | R | 51 | 71 | 0 | 6 | 1 | 3.97 | .273 | 1.07 | 6.4 | 3.3 | 9.7 | 65.2 | 46 | 29 | 29 | 8 | 24 | 70 | 0 | 0 | 2 | 0 | 0 | 4 | 1 | 3.74 |
| RP | Wendell, T.Wendell, Turk >> | 36 | 2003 | R | 36 | 50 | 0 | 0 | 2 | 5.74 | .359 | 1.61 | 10.5 | 4.1 | 5.1 | 42.1 | 49 | 28 | 27 | 11 | 19 | 24 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 6.83 |
| RP | de los Santos, V.de los Santos, Valerio >> | 31 | 2003 | L | 33 | 60 | 0 | 2 | 2 | 5.76 | .349 | 1.59 | 9.2 | 5.3 | 9.0 | 54.2 | 55 | 36 | 35 | 9 | 32 | 54 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 5.00 |
| SP | Telemaco, A.Telemaco, Amaury >> | 29 | 2003 | R | 54 | 31 | 0 | 3 | 2 | 4.50 | .321 | 1.40 | 9.1 | 3.5 | 5.7 | 106.0 | 107 | 53 | 53 | 13 | 41 | 67 | 0 | 2 | 1 | 0 | 0 | 2 | 3 | 4.55 |