| SP | Walker, T.Walker, Taijuan >> | 27 | 2014 | R | 100 | 23 | 23 | 12 | 5 | 2.21 | .251 | 0.98 | 5.7 | 3.2 | 9.6 | 171.1 | 108 | 42 | 42 | 6 | 60 | 182 | 1 | 0 | 0 | 1 | 19 | 4 | 1 | 2.45 |
| SP | Gsellman, R.Gsellman, Robert >> | 30 | 2016 | R | 99 | 23 | 23 | 13 | 6 | 3.53 | .272 | 1.10 | 6.6 | 3.3 | 6.9 | 168.1 | 123 | 67 | 66 | 18 | 62 | 129 | 3 | 0 | 0 | 2 | 15 | 4 | 2 | 4.04 |
| SP | Montero, R.Montero, Rafael >> | 29 | 2014 | R | 88 | 23 | 23 | 14 | 4 | 2.75 | .245 | 0.94 | 6.3 | 2.2 | 9.6 | 153.2 | 107 | 47 | 47 | 15 | 37 | 163 | 0 | 0 | 0 | 0 | 16 | 6 | 0 | 2.99 |
| SP | Scherzer, M.Scherzer, Max >> | 34 | 2013 | R | 80 | 23 | 23 | 12 | 5 | 3.68 | .288 | 1.21 | 8.0 | 2.9 | 10.4 | 156.1 | 139 | 69 | 64 | 14 | 50 | 181 | 3 | 0 | 0 | 2 | 12 | 1 | 1 | 2.83 |
| SP | deGrom, J.deGrom, Jacob # >> | 34 | 2015 | R | 77 | 22 | 22 | 8 | 7 | 4.10 | .267 | 1.06 | 7.9 | 1.7 | 9.1 | 151.1 | 132 | 71 | 69 | 19 | 29 | 153 | 1 | 0 | 0 | 1 | 12 | 4 | 2 | 3.26 |
| RP | Familia, J.Familia, Jeurys >> | 30 | 2014 | R | 86 | 66 | 0 | 3 | 2 | 2.64 | .238 | 0.91 | 5.0 | 3.3 | 6.6 | 88.2 | 49 | 27 | 26 | 5 | 32 | 65 | 0 | 6 | 2 | 0 | 0 | 2 | 3 | 3.42 |
| RP | Salas, F.Salas, Fernando >> | 29 | 2011 | R | 86 | 34 | 0 | 3 | 2 | 3.63 | .320 | 1.41 | 9.3 | 3.7 | 8.7 | 34.2 | 35 | 14 | 14 | 4 | 14 | 33 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.82 |
| RP | Bastardo, A.Bastardo, Antonio >> | 29 | 2011 | L | 96 | 19 | 0 | 2 | 0 | 0.72 | .202 | 0.76 | 4.0 | 2.9 | 10.8 | 25.0 | 11 | 2 | 2 | 1 | 8 | 30 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.08 |
| RP | Grimm, J.Grimm, Justin >> | 33 | 2015 | R | 78 | 8 | 0 | 2 | 1 | 5.63 | .294 | 1.25 | 6.8 | 4.5 | 12.4 | 8.0 | 6 | 5 | 5 | 2 | 4 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.00 |
| RP | Blevins, J.Blevins, Jerry >> | 25 | 2008 | L | 38 | 12 | 0 | 0 | 0 | 4.15 | .328 | 1.46 | 10.4 | 2.8 | 4.2 | 13.0 | 15 | 6 | 6 | 2 | 4 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| SP | Peterson, D.Peterson, David >> | 36 | 2020 | L | 60 | 1 | 0 | 0 | 0 | 3.00 | .217 | 0.83 | 6.0 | 1.5 | 9.0 | 6.0 | 4 | 2 | 2 | 1 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.67 |