| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 16 | 27 | 27 | 12 | 10 | 5.09 | .334 | 1.47 | 10.0 | 3.4 | 4.8 | 169.2 | 187 | 97 | 96 | 23 | 63 | 90 | 4 | 0 | 0 | 0 | 12 | 5 | 6 | 4.91 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 11 | 19 | 17 | 4 | 7 | 4.87 | .348 | 1.59 | 10.5 | 3.9 | 5.4 | 105.1 | 122 | 63 | 57 | 12 | 46 | 63 | 2 | 1 | 0 | 0 | 10 | 1 | 2 | 4.63 |
| SP | Strasburg, S.Strasburg, Stephen >> | 22 | 2011 | R | 76 | 26 | 26 | 9 | 3 | 4.77 | .330 | 1.48 | 11.1 | 2.3 | 6.6 | 128.1 | 158 | 73 | 68 | 7 | 32 | 94 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 2.99 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 50 | 21 | 21 | 7 | 7 | 6.14 | .367 | 1.67 | 12.0 | 3.0 | 8.6 | 110.0 | 147 | 85 | 75 | 15 | 37 | 105 | 2 | 0 | 0 | 1 | 6 | 7 | 3 | 4.06 |
| SP | Paige, S.Paige, Satchel >> | 27 | 1933 | R | 54 | 19 | 19 | 8 | 3 | 5.84 | .352 | 1.61 | 11.6 | 3.0 | 6.1 | 101.2 | 130 | 67 | 66 | 4 | 34 | 68 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 3.24 |
| RP | Dayton, G.Dayton, Grant >> | 28 | 2016 | L | 55 | 67 | 0 | 2 | 0 | 3.19 | .288 | 1.15 | 7.5 | 2.9 | 8.4 | 59.1 | 49 | 26 | 21 | 7 | 19 | 55 | 0 | 1 | 1 | 0 | 0 | 4 | 0 | 3.85 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 61 | 65 | 0 | 4 | 3 | 5.88 | .356 | 1.64 | 11.4 | 3.5 | 9.8 | 59.2 | 75 | 42 | 39 | 6 | 23 | 64 | 0 | 15 | 3 | 0 | 0 | 1 | 0 | 3.37 |
| RP | Garcia, Y.Garcia, Yimi >> | 29 | 2020 | R | 19 | 47 | 0 | 2 | 3 | 5.44 | .354 | 1.65 | 9.9 | 4.9 | 7.7 | 48.0 | 53 | 29 | 29 | 4 | 26 | 41 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Jansen, K.Jansen, Kenley >> | 29 | 2017 | R | 46 | 44 | 0 | 1 | 1 | 1.77 | .263 | 1.01 | 6.6 | 2.6 | 9.2 | 45.2 | 33 | 16 | 9 | 1 | 13 | 46 | 0 | 8 | 1 | 0 | 0 | 3 | 0 | 2.31 |
| SP | Schupp, F.Schupp, Ferdie >> | 25 | 1916 | L | 57 | 6 | 1 | 1 | 1 | 8.53 | .356 | 1.50 | 11.3 | 3.0 | 5.3 | 12.2 | 15 | 12 | 12 | 1 | 4 | 7 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.42 |
| SU | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 25 | 41 | 0 | 2 | 3 | 5.75 | .378 | 1.82 | 10.4 | 6.3 | 7.4 | 40.2 | 46 | 29 | 26 | 5 | 28 | 33 | 0 | 1 | 3 | 0 | 0 | 0 | 3 | 5.08 |