| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 17 | 23 | 23 | 12 | 7 | 4.60 | .323 | 1.40 | 9.4 | 3.2 | 4.6 | 154.2 | 161 | 80 | 79 | 18 | 55 | 79 | 4 | 0 | 0 | 0 | 12 | 5 | 5 | 4.66 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 11 | 16 | 14 | 3 | 5 | 4.48 | .349 | 1.59 | 10.6 | 3.8 | 5.4 | 90.1 | 106 | 51 | 45 | 11 | 38 | 54 | 2 | 1 | 0 | 0 | 9 | 1 | 1 | 4.69 |
| SP | Strasburg, S.Strasburg, Stephen >> | 22 | 2011 | R | 75 | 23 | 23 | 8 | 3 | 5.02 | .330 | 1.48 | 11.1 | 2.2 | 6.5 | 113.0 | 139 | 64 | 63 | 7 | 28 | 82 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 3.10 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 50 | 19 | 19 | 7 | 6 | 5.69 | .359 | 1.62 | 11.7 | 2.9 | 8.7 | 106.0 | 138 | 77 | 67 | 14 | 34 | 102 | 2 | 0 | 0 | 1 | 6 | 6 | 3 | 3.92 |
| SP | Paige, S.Paige, Satchel >> | 27 | 1933 | R | 54 | 16 | 16 | 7 | 3 | 5.76 | .352 | 1.60 | 11.6 | 2.8 | 6.5 | 86.0 | 111 | 56 | 55 | 3 | 27 | 62 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 3.02 |
| RP | Dayton, G.Dayton, Grant >> | 28 | 2016 | L | 54 | 58 | 0 | 2 | 0 | 3.49 | .286 | 1.16 | 7.9 | 2.6 | 8.1 | 49.0 | 43 | 24 | 19 | 5 | 14 | 44 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.51 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 62 | 56 | 0 | 4 | 2 | 5.51 | .359 | 1.66 | 11.3 | 3.8 | 9.5 | 50.2 | 63 | 33 | 31 | 3 | 21 | 53 | 0 | 15 | 2 | 0 | 0 | 1 | 0 | 2.98 |
| RP | Garcia, Y.Garcia, Yimi >> | 29 | 2020 | R | 20 | 39 | 0 | 2 | 2 | 4.95 | .337 | 1.53 | 9.7 | 4.1 | 7.4 | 40.0 | 43 | 22 | 22 | 3 | 18 | 33 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.68 |
| RP | Jansen, K.Jansen, Kenley >> | 29 | 2017 | R | 47 | 38 | 0 | 1 | 1 | 1.89 | .274 | 1.05 | 6.4 | 3.1 | 8.5 | 38.0 | 27 | 13 | 8 | 1 | 13 | 36 | 0 | 8 | 1 | 0 | 0 | 3 | 0 | 2.71 |
| SP | Schupp, F.Schupp, Ferdie >> | 25 | 1916 | L | 56 | 6 | 1 | 1 | 1 | 8.53 | .356 | 1.50 | 11.3 | 3.0 | 5.3 | 12.2 | 15 | 12 | 12 | 1 | 4 | 7 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.42 |
| SU | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 26 | 34 | 0 | 2 | 3 | 6.09 | .389 | 1.91 | 10.6 | 6.6 | 7.4 | 34.0 | 40 | 26 | 23 | 4 | 25 | 28 | 0 | 1 | 3 | 0 | 0 | 0 | 3 | 5.09 |