| SP | Hill, R.Hill, Rich >> | 35 | 2015 | L | 94 | 21 | 21 | 11 | 4 | 4.28 | .311 | 1.32 | 9.2 | 2.8 | 7.5 | 136.2 | 139 | 73 | 65 | 17 | 42 | 114 | 5 | 0 | 0 | 1 | 11 | 4 | 0 | 3.96 |
| SP | Sanchez, A.Sanchez, Aaron >> | 21 | 2014 | R | 91 | 8 | 0 | 0 | 1 | 3.97 | .244 | 0.97 | 6.5 | 2.5 | 5.7 | 11.1 | 8 | 6 | 5 | 2 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.91 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 20 | 1980 | L | 77 | 19 | 19 | 7 | 4 | 5.12 | .321 | 1.39 | 8.0 | 4.6 | 9.1 | 114.1 | 101 | 66 | 65 | 11 | 58 | 115 | 5 | 0 | 0 | 0 | 8 | 3 | 0 | 3.84 |
| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 80 | 21 | 21 | 8 | 8 | 5.36 | .344 | 1.56 | 11.1 | 3.0 | 10.7 | 122.2 | 151 | 84 | 73 | 13 | 40 | 145 | 3 | 0 | 0 | 0 | 10 | 2 | 1 | 3.04 |
| SP | Coveleski, H.Coveleski, Harry >> | 21 | 1907 | L | 86 | 9 | 5 | 3 | 1 | 5.80 | .331 | 1.49 | 10.3 | 3.3 | 6.2 | 35.2 | 40 | 28 | 23 | 6 | 13 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.97 |
| RP | Clase, E.Clase, Emmanuel >> | 26 | 2024 | R | 72 | 30 | 0 | 2 | 1 | 5.12 | .326 | 1.45 | 10.7 | 2.6 | 5.8 | 31.2 | 37 | 18 | 18 | 3 | 9 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.84 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 92 | 33 | 0 | 1 | 1 | 4.79 | .301 | 1.26 | 9.8 | 1.8 | 7.5 | 35.2 | 38 | 19 | 19 | 3 | 7 | 29 | 0 | 3 | 5 | 0 | 0 | 1 | 0 | 3.14 |
| RP | Fairbanks, P.Fairbanks, Peter >> | 28 | 2022 | R | 76 | 9 | 2 | 2 | 1 | 8.44 | .400 | 1.94 | 11.8 | 5.6 | 10.1 | 16.0 | 21 | 17 | 15 | 1 | 10 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.63 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 78 | 22 | 0 | 4 | 2 | 3.86 | .233 | 0.91 | 6.5 | 2.0 | 11.5 | 18.2 | 13 | 8 | 8 | 3 | 4 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.28 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 77 | 35 | 0 | 1 | 4 | 4.34 | .329 | 1.42 | 8.0 | 4.9 | 8.3 | 37.1 | 33 | 18 | 18 | 2 | 20 | 34 | 0 | 3 | 4 | 0 | 0 | 2 | 6 | 3.65 |
| SP | Means, J.Means, John >> | 30 | 2023 | L | 71 | 9 | 0 | 1 | 1 | 3.09 | .314 | 1.33 | 9.8 | 2.3 | 4.2 | 43.2 | 47 | 23 | 15 | 2 | 11 | 20 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.58 |
| SP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 90 | 12 | 12 | 5 | 3 | 4.54 | .323 | 1.39 | 10.1 | 2.4 | 8.0 | 71.1 | 80 | 39 | 36 | 7 | 19 | 63 | 1 | 0 | 0 | 1 | 7 | 3 | 0 | 3.44 |
| SP | McQuillan, G.McQuillan, George >> | 22 | 1907 | R | 68 | 4 | 3 | 1 | 1 | 10.22 | .431 | 2.27 | 15.0 | 6.0 | 4.5 | 12.1 | 20 | 14 | 14 | 2 | 8 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.17 |
| SP | de los Santos, V.de los Santos, Valerio >> | 26 | 1998 | L | 92 | 10 | 2 | 1 | 1 | 8.59 | .421 | 2.18 | 16.7 | 3.9 | 8.4 | 14.2 | 26 | 15 | 14 | 2 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.29 |
| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 79 | 17 | 17 | 5 | 7 | 6.48 | .363 | 1.67 | 11.7 | 3.5 | 9.0 | 91.2 | 118 | 68 | 66 | 13 | 35 | 91 | 1 | 0 | 0 | 0 | 6 | 4 | 3 | 4.14 |
| SP | McDowell, J.McDowell, Jack >> | 21 | 1987 | R | 61 | 10 | 0 | 2 | 1 | 3.88 | .305 | 1.25 | 8.8 | 2.5 | 3.5 | 46.1 | 45 | 21 | 20 | 4 | 13 | 18 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 4.39 |
| SP | Walker, G.Walker, George >> | 25 | 1940 | R | 72 | 6 | 0 | 0 | 1 | 3.79 | .313 | 1.37 | 9.9 | 2.4 | 4.7 | 19.0 | 21 | 8 | 8 | 2 | 5 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.11 |