| SP | Hill, R.Hill, Rich >> | 35 | 2015 | L | 95 | 24 | 24 | 12 | 5 | 4.24 | .306 | 1.29 | 9.1 | 2.6 | 7.8 | 155.0 | 156 | 81 | 73 | 20 | 44 | 134 | 5 | 0 | 0 | 1 | 12 | 5 | 0 | 3.90 |
| SP | Sanchez, A.Sanchez, Aaron >> | 21 | 2014 | R | 91 | 12 | 4 | 2 | 2 | 5.24 | .335 | 1.49 | 9.3 | 4.2 | 5.0 | 34.1 | 35 | 21 | 20 | 7 | 16 | 19 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 6.06 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 20 | 1980 | L | 77 | 22 | 22 | 10 | 4 | 5.27 | .318 | 1.38 | 7.9 | 4.5 | 9.5 | 135.0 | 118 | 80 | 79 | 15 | 68 | 143 | 6 | 0 | 0 | 0 | 8 | 3 | 0 | 3.90 |
| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 80 | 24 | 24 | 10 | 9 | 5.29 | .339 | 1.51 | 10.7 | 2.9 | 10.6 | 146.1 | 174 | 97 | 86 | 15 | 47 | 172 | 4 | 0 | 0 | 0 | 11 | 4 | 1 | 3.03 |
| SP | Coveleski, H.Coveleski, Harry >> | 21 | 1907 | L | 86 | 11 | 7 | 4 | 2 | 5.21 | .330 | 1.48 | 9.4 | 4.1 | 5.9 | 46.2 | 48 | 32 | 27 | 8 | 21 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.33 |
| RP | Clase, E.Clase, Emmanuel >> | 26 | 2024 | R | 70 | 36 | 0 | 2 | 1 | 5.85 | .326 | 1.43 | 10.4 | 2.5 | 6.3 | 40.0 | 46 | 26 | 26 | 4 | 11 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.80 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 93 | 40 | 0 | 1 | 1 | 5.88 | .315 | 1.35 | 10.1 | 2.2 | 7.7 | 41.1 | 46 | 27 | 27 | 6 | 10 | 35 | 0 | 3 | 5 | 0 | 0 | 1 | 0 | 4.00 |
| RP | Fairbanks, P.Fairbanks, Peter >> | 28 | 2022 | R | 75 | 15 | 2 | 2 | 1 | 6.08 | .355 | 1.61 | 10.2 | 4.7 | 11.3 | 23.2 | 26 | 18 | 16 | 1 | 12 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.74 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 78 | 27 | 0 | 4 | 3 | 4.30 | .258 | 1.04 | 6.7 | 2.7 | 11.0 | 23.0 | 17 | 11 | 11 | 5 | 7 | 28 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.30 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 76 | 38 | 0 | 1 | 4 | 4.05 | .314 | 1.33 | 7.4 | 4.5 | 7.9 | 40.0 | 33 | 18 | 18 | 2 | 20 | 35 | 0 | 5 | 4 | 0 | 0 | 2 | 7 | 3.55 |
| SP | Means, J.Means, John >> | 30 | 2023 | L | 72 | 9 | 0 | 1 | 1 | 3.09 | .314 | 1.33 | 9.8 | 2.3 | 4.2 | 43.2 | 47 | 23 | 15 | 2 | 11 | 20 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.58 |
| SP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 92 | 12 | 12 | 5 | 3 | 4.54 | .323 | 1.39 | 10.1 | 2.4 | 8.0 | 71.1 | 80 | 39 | 36 | 7 | 19 | 63 | 1 | 0 | 0 | 1 | 7 | 3 | 0 | 3.44 |
| SP | Northrop, J.Northrop, Jake >> | 30 | 1918 | R | 61 | 8 | 5 | 3 | 2 | 5.86 | .346 | 1.58 | 12.3 | 2.1 | 2.8 | 35.1 | 48 | 23 | 23 | 5 | 8 | 11 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 4.91 |
| SP | de los Santos, V.de los Santos, Valerio >> | 26 | 1998 | L | 92 | 10 | 2 | 1 | 1 | 8.59 | .421 | 2.18 | 16.7 | 3.9 | 8.4 | 14.2 | 26 | 15 | 14 | 2 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.29 |
| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 79 | 17 | 17 | 5 | 7 | 6.48 | .363 | 1.67 | 11.7 | 3.5 | 9.0 | 91.2 | 118 | 68 | 66 | 13 | 35 | 91 | 1 | 0 | 0 | 0 | 6 | 4 | 3 | 4.14 |
| SP | McDowell, J.McDowell, Jack >> | 21 | 1987 | R | 62 | 11 | 0 | 2 | 1 | 4.17 | .307 | 1.27 | 9.0 | 2.6 | 3.9 | 49.2 | 49 | 24 | 23 | 4 | 14 | 21 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 4.24 |
| SP | Walker, G.Walker, George >> | 25 | 1940 | R | 73 | 7 | 0 | 1 | 1 | 4.24 | .333 | 1.50 | 11.0 | 2.7 | 5.1 | 23.1 | 28 | 12 | 11 | 3 | 7 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.48 |