| SP | Cushman, E.Cushman, Ed >> | 32 | 1884 | L | 100 | 27 | 27 | 16 | 5 | 2.76 | .254 | 1.01 | 7.2 | 1.9 | 7.7 | 198.2 | 159 | 64 | 61 | 16 | 41 | 169 | 10 | 0 | 0 | 2 | 21 | 3 | 0 | 3.01 |
| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 98 | 27 | 27 | 14 | 6 | 3.84 | .295 | 1.23 | 7.9 | 3.2 | 8.8 | 150.0 | 132 | 69 | 64 | 16 | 53 | 146 | 0 | 0 | 0 | 0 | 19 | 3 | 0 | 3.56 |
| SP | Baldwin, L.Baldwin, Lady >> | 25 | 1884 | L | 99 | 26 | 26 | 13 | 6 | 3.99 | .299 | 1.26 | 8.7 | 2.6 | 9.0 | 176.0 | 170 | 78 | 78 | 17 | 51 | 176 | 8 | 0 | 0 | 0 | 15 | 4 | 0 | 3.19 |
| SP | Hooton, B.Hooton, Burt >> | 21 | 1971 | R | 65 | 23 | 23 | 14 | 3 | 4.83 | .355 | 1.64 | 8.4 | 6.4 | 7.1 | 130.1 | 122 | 75 | 70 | 14 | 92 | 102 | 0 | 0 | 0 | 0 | 10 | 1 | 3 | 4.98 |
| RP | Furbush, C.Furbush, Charlie >> | 29 | 2015 | L | 79 | 46 | 0 | 3 | 2 | 3.51 | .259 | 0.99 | 6.3 | 2.7 | 5.5 | 56.1 | 39 | 24 | 22 | 5 | 17 | 34 | 0 | 1 | 1 | 0 | 0 | 3 | 10 | 4.02 |
| RP | Hendriks, L.Hendriks, Liam >> | 31 | 2020 | R | 69 | 41 | 0 | 4 | 1 | 4.68 | .355 | 1.61 | 11.4 | 3.2 | 8.1 | 42.1 | 53 | 24 | 22 | 4 | 15 | 38 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 3.64 |
| SU | Williams, D.Williams, Devin >> | 25 | 2020 | R | 100 | 48 | 0 | 2 | 1 | 4.80 | .333 | 1.48 | 7.0 | 6.5 | 11.7 | 50.2 | 39 | 27 | 27 | 4 | 36 | 65 | 0 | 4 | 3 | 0 | 0 | 1 | 4 | 3.66 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 91 | 43 | 0 | 0 | 1 | 2.36 | .227 | 0.86 | 4.7 | 3.0 | 10.1 | 42.0 | 22 | 12 | 11 | 4 | 14 | 47 | 0 | 31 | 2 | 0 | 0 | 1 | 2 | 3.07 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 19 | 3 | 1 | 1 | 0 | 2.84 | .283 | 1.18 | 6.8 | 4.5 | 7.5 | 12.2 | 9 | 4 | 4 | 0 | 6 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.83 |
| SP | Gonzalez, V.Gonzalez, Victor >> | 24 | 2020 | L | 66 | 12 | 11 | 5 | 1 | 6.83 | .341 | 1.50 | 10.6 | 2.9 | 8.4 | 58.0 | 68 | 49 | 44 | 8 | 19 | 54 | 3 | 0 | 0 | 0 | 4 | 3 | 4 | 4.07 |
| SP | Cotton, J.Cotton, Jharel >> | 24 | 2016 | R | 47 | 16 | 4 | 5 | 1 | 5.18 | .329 | 1.45 | 10.6 | 2.5 | 4.5 | 66.0 | 78 | 38 | 38 | 8 | 18 | 33 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 4.44 |
| SP | Maddox, N.Maddox, Nick >> | 21 | 1907 | R | 55 | 1 | 0 | 0 | 1 | 6.35 | .370 | 1.76 | 14.4 | 3.6 | 7.2 | 5.2 | 8 | 6 | 4 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.60 |
| SP | Perez, O.Perez, Oliver >> | 37 | 2018 | L | 84 | 15 | 13 | 8 | 2 | 4.17 | .334 | 1.46 | 9.5 | 3.7 | 8.5 | 86.1 | 91 | 43 | 40 | 5 | 35 | 81 | 1 | 0 | 0 | 0 | 8 | 4 | 1 | 3.23 |