| SP | Baldwin, L.Baldwin, Lady >> | 25 | 1884 | L | 99 | 24 | 24 | 12 | 5 | 3.95 | .295 | 1.24 | 8.6 | 2.6 | 9.1 | 166.1 | 158 | 73 | 73 | 17 | 48 | 168 | 8 | 0 | 0 | 0 | 14 | 3 | 0 | 3.23 |
| SP | Perez, O.Perez, Oliver >> | 37 | 2018 | L | 84 | 14 | 13 | 7 | 2 | 4.17 | .333 | 1.46 | 9.5 | 3.6 | 8.5 | 82.0 | 87 | 41 | 38 | 5 | 33 | 77 | 1 | 0 | 0 | 0 | 8 | 3 | 1 | 3.23 |
| SP | Hooton, B.Hooton, Burt >> | 21 | 1971 | R | 65 | 20 | 20 | 12 | 3 | 4.63 | .349 | 1.60 | 8.3 | 6.2 | 7.6 | 112.2 | 103 | 63 | 58 | 11 | 77 | 94 | 0 | 0 | 0 | 0 | 9 | 1 | 2 | 4.69 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 20 | 1980 | L | 77 | 19 | 19 | 7 | 4 | 5.12 | .321 | 1.39 | 8.0 | 4.6 | 9.1 | 114.1 | 101 | 66 | 65 | 11 | 58 | 115 | 5 | 0 | 0 | 0 | 8 | 3 | 0 | 3.84 |
| RP | Furbush, C.Furbush, Charlie >> | 29 | 2015 | L | 80 | 37 | 0 | 3 | 2 | 3.11 | .245 | 0.91 | 5.7 | 2.5 | 4.9 | 46.1 | 29 | 16 | 16 | 4 | 13 | 25 | 0 | 1 | 1 | 0 | 0 | 3 | 9 | 4.09 |
| RP | Hendriks, L.Hendriks, Liam >> | 31 | 2020 | R | 71 | 36 | 0 | 4 | 1 | 4.97 | .345 | 1.53 | 11.8 | 1.9 | 7.8 | 38.0 | 50 | 23 | 21 | 4 | 8 | 33 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 3.42 |
| SU | Williams, D.Williams, Devin >> | 25 | 2020 | R | 100 | 40 | 0 | 2 | 1 | 5.74 | .342 | 1.54 | 7.7 | 6.2 | 11.8 | 42.1 | 36 | 27 | 27 | 4 | 29 | 55 | 0 | 4 | 3 | 0 | 0 | 1 | 3 | 3.76 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 91 | 37 | 0 | 0 | 1 | 2.27 | .219 | 0.84 | 4.6 | 3.1 | 10.5 | 35.2 | 18 | 10 | 9 | 3 | 12 | 41 | 0 | 26 | 2 | 0 | 0 | 0 | 2 | 2.80 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 18 | 2 | 0 | 1 | 0 | 0.73 | .229 | 0.89 | 4.5 | 3.8 | 7.5 | 12.1 | 6 | 1 | 1 | 0 | 5 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.58 |
| SP | Gonzalez, V.Gonzalez, Victor >> | 24 | 2020 | L | 67 | 12 | 11 | 5 | 1 | 6.83 | .341 | 1.50 | 10.6 | 2.9 | 8.4 | 58.0 | 68 | 49 | 44 | 8 | 19 | 54 | 3 | 0 | 0 | 0 | 4 | 3 | 4 | 4.07 |
| SP | Maddox, N.Maddox, Nick >> | 21 | 1907 | R | 55 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 20 | 13 | 13 | 3 | 8 | 9.25 | .427 | 2.24 | 14.3 | 6.0 | 4.8 | 60.1 | 95 | 74 | 62 | 10 | 40 | 32 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 6.10 |
| SP | Coveleski, H.Coveleski, Harry >> | 21 | 1907 | L | 86 | 9 | 5 | 3 | 1 | 5.80 | .331 | 1.49 | 10.3 | 3.3 | 6.2 | 35.2 | 40 | 28 | 23 | 6 | 13 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.97 |