| SP | Strasburg, S.Strasburg, Stephen >> | 22 | 2011 | R | 71 | 10 | 10 | 2 | 2 | 5.79 | .336 | 1.46 | 11.1 | 2.1 | 5.8 | 51.1 | 63 | 33 | 33 | 6 | 12 | 33 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 4.12 |
| SP | Schupp, F.Schupp, Ferdie >> | 25 | 1916 | L | 50 | 10 | 10 | 1 | 3 | 6.60 | .371 | 1.73 | 11.5 | 4.1 | 4.9 | 46.1 | 59 | 34 | 34 | 4 | 21 | 25 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 4.54 |
| SP | Paige, S.Paige, Satchel >> | 27 | 1933 | R | 46 | 9 | 9 | 2 | 5 | 7.24 | .364 | 1.70 | 10.2 | 5.3 | 3.8 | 54.2 | 61 | 45 | 44 | 5 | 32 | 23 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 5.19 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 41 | 7 | 7 | 1 | 3 | 8.08 | .374 | 1.74 | 14.1 | 1.6 | 6.5 | 39.0 | 61 | 35 | 35 | 7 | 7 | 28 | 1 | 0 | 0 | 0 | 1 | 2 | 2 | 4.59 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 60 | 26 | 0 | 1 | 4 | 10.13 | .394 | 1.91 | 13.8 | 3.8 | 9.3 | 26.2 | 40 | 33 | 30 | 5 | 11 | 27 | 0 | 0 | 3 | 0 | 0 | 1 | 2 | 4.81 |
| RP | Dayton, G.Dayton, Grant >> | 28 | 2016 | L | 53 | 19 | 0 | 2 | 0 | 8.31 | .404 | 1.94 | 10.3 | 7.7 | 6.9 | 21.2 | 24 | 20 | 20 | 5 | 18 | 16 | 0 | 0 | 3 | 0 | 0 | 2 | 0 | 7.43 |
| RP | Jansen, K.Jansen, Kenley >> | 29 | 2017 | R | 45 | 20 | 0 | 1 | 2 | 9.41 | .400 | 2.00 | 15.5 | 2.5 | 8.2 | 22.0 | 38 | 23 | 23 | 8 | 6 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.73 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 25 | 13 | 0 | 1 | 0 | 5.56 | .424 | 2.21 | 12.3 | 8.2 | 8.2 | 11.1 | 15 | 7 | 7 | 1 | 10 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 5.09 |
| RP | Garcia, Y.Garcia, Yimi >> | 29 | 2020 | R | 18 | 12 | 0 | 1 | 0 | 5.74 | .319 | 1.40 | 11.4 | 1.8 | 7.8 | 15.2 | 19 | 10 | 10 | 4 | 3 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.33 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 6 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 11 | 3 | 0 | 1 | 0 | 7.59 | .396 | 1.97 | 12.6 | 6.3 | 4.5 | 10.2 | 14 | 12 | 9 | 2 | 7 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 6.70 |