| SP | Cotton, J.Cotton, Jharel >> | 24 | 2016 | R | 79 | 19 | 19 | 10 | 3 | 5.04 | .327 | 1.43 | 9.6 | 3.3 | 4.0 | 109.0 | 116 | 63 | 61 | 13 | 40 | 49 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 4.83 |
| SP | Skubal, T.Skubal, Tarik >> | 26 | 2023 | L | 63 | 18 | 18 | 4 | 10 | 5.87 | .368 | 1.69 | 12.3 | 3.0 | 7.2 | 96.2 | 131 | 70 | 63 | 17 | 32 | 77 | 0 | 0 | 0 | 0 | 2 | 6 | 2 | 4.89 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 48 | 14 | 14 | 10 | 2 | 3.52 | .300 | 1.24 | 7.7 | 3.5 | 4.3 | 99.2 | 85 | 39 | 39 | 5 | 39 | 47 | 1 | 0 | 0 | 0 | 9 | 4 | 0 | 4.01 |
| SU | Sadler, C.Sadler, Casey >> | 30 | 2021 | R | 71 | 29 | 0 | 0 | 2 | 2.45 | .302 | 1.30 | 7.1 | 4.7 | 5.3 | 29.1 | 23 | 8 | 8 | 2 | 15 | 17 | 0 | 3 | 3 | 0 | 0 | 0 | 1 | 4.28 |
| RP | Johnston, J.Johnston, Joel >> | 24 | 1991 | R | 58 | 42 | 0 | 5 | 1 | 2.56 | .299 | 1.26 | 5.9 | 5.6 | 5.1 | 63.1 | 41 | 20 | 18 | 2 | 39 | 36 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 4.17 |
| CL | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 37 | 34 | 0 | 3 | 4 | 3.38 | .267 | 1.06 | 7.3 | 2.3 | 7.6 | 32.0 | 26 | 12 | 12 | 1 | 8 | 27 | 0 | 20 | 1 | 0 | 0 | 1 | 1 | 2.56 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 38 | 33 | 0 | 3 | 2 | 3.34 | .314 | 1.34 | 7.2 | 4.9 | 7.2 | 35.0 | 28 | 13 | 13 | 2 | 19 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.86 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 44 | 3 | 0 | 0 | 0 | 10.45 | .446 | 2.42 | 19.8 | 2.7 | 4.5 | 10.1 | 22 | 12 | 12 | 2 | 3 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.50 |