| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 8 | 8 | 4 | 3 | 5.05 | .346 | 1.56 | 10.3 | 3.7 | 10.8 | 41.0 | 47 | 25 | 23 | 6 | 17 | 49 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 3.83 |
| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 89 | 8 | 8 | 2 | 4 | 6.63 | .360 | 1.66 | 11.8 | 3.1 | 9.2 | 38.0 | 50 | 29 | 28 | 11 | 13 | 39 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 5.82 |
| SP | Houck, T.Houck, Tanner >> | 24 | 2020 | R | 72 | 8 | 8 | 3 | 4 | 4.50 | .371 | 1.75 | 9.2 | 6.5 | 8.0 | 44.0 | 45 | 22 | 22 | 5 | 32 | 39 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 4.95 |
| SP | Bieber, S.Bieber, Shane >> | 25 | 2020 | R | 63 | 6 | 6 | 2 | 3 | 5.97 | .326 | 1.45 | 9.6 | 3.8 | 10.7 | 31.2 | 33 | 21 | 21 | 9 | 13 | 37 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 5.65 |
| SP | Gonsolin, T.Gonsolin, Tony >> | 28 | 2022 | R | 54 | 6 | 6 | 2 | 3 | 8.88 | .411 | 2.01 | 11.6 | 6.8 | 6.8 | 24.1 | 31 | 24 | 24 | 4 | 18 | 18 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 6.17 |
| CL | Anderson, N.Anderson, Nick >> | 29 | 2020 | R | 100 | 10 | 0 | 1 | 0 | 0.87 | .139 | 0.48 | 1.8 | 2.7 | 9.9 | 10.1 | 2 | 1 | 1 | 0 | 3 | 11 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 1.70 |
| SU | Hennis, R.Hennis, Randy >> | 25 | 1990 | R | 97 | 12 | 0 | 0 | 0 | 1.99 | .299 | 1.24 | 3.7 | 7.8 | 5.7 | 22.2 | 9 | 5 | 5 | 1 | 19 | 14 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 5.05 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 84 | 16 | 0 | 1 | 0 | 4.67 | .288 | 1.15 | 7.4 | 3.2 | 9.5 | 17.1 | 14 | 9 | 9 | 1 | 6 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.88 |
| RP | Gossage, G.Gossage, Goose >> | 30 | 1981 | R | 69 | 14 | 0 | 0 | 0 | 3.46 | .304 | 1.31 | 6.2 | 5.5 | 5.5 | 13.0 | 9 | 5 | 5 | 0 | 8 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.62 |
| RP | Franco, J.Franco, John >> | 28 | 1988 | L | 4 | 22 | 0 | 2 | 1 | 5.30 | .364 | 1.66 | 11.5 | 4.0 | 6.5 | 18.2 | 23 | 11 | 11 | 5 | 8 | 13 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 6.67 |
| SP | Clemens, R.Clemens, Roger >> | 35 | 1997 | R | 19 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 42 | 2 | 0 | 0 | 0 | 0.00 | .333 | 1.50 | 9.0 | 4.5 | 4.5 | 2.0 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.50 |
| SP | Yamamoto, Y.Yamamoto, Yoshinobu >> | 27 | 2026 | R | 52 | 10 | 0 | 1 | 0 | 3.26 | .270 | 1.09 | 8.3 | 1.7 | 6.6 | 38.2 | 35 | 19 | 14 | 5 | 7 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.87 |